Epigenome-wide DNA methylation analysis of myasthenia gravis.
Sign Up to like & getrecommendations! Published in 2023 at "FEBS open bio"
DOI: 10.1002/2211-5463.13656
Abstract: Myasthenia gravis (MG) is a common neuromuscular junction (NMJ) disorder and autoimmune disease mediated by several antibodies. Several studies have shown that genetic factors play an important role in MG pathogenesis. To gain insight into… read more here.
Keywords: methylation; methylation analysis; dna methylation; wide dna ... See more keywords
Comprehensive structural analysis of a set of various branched glucans by standard methylation analysis, 1H NMR spectroscopy, ESI-mass spectrometry, and capillary electrophoresis.
Sign Up to like & getrecommendations! Published in 2020 at "Carbohydrate research"
DOI: 10.1016/j.carres.2020.107933
Abstract: Various (semi)-synthetic non-digestible glucans (NDG) (resistant (malto)dextrin, isomaltooligosaccharide, soluble corn fiber, polydextrose) were analyzed by methylation analysis, 1H NMR spectroscopy, ESI-MSn, TLC, and capillary electrophoresis (CE/UV). Partly complementary and partly corroborative results were obtained by… read more here.
Keywords: analysis; nmr spectroscopy; electrophoresis; spectroscopy ... See more keywords
Detection of colorectal cancer in urine using DNA methylation analysis
Sign Up to like & getrecommendations! Published in 2021 at "Scientific Reports"
DOI: 10.1038/s41598-021-81900-6
Abstract: Colorectal cancer (CRC) is the second leading cause for cancer-related death globally. Clinically, there is an urgent need for non-invasive CRC detection. This study assessed the feasibility of CRC detection by analysis of tumor-derived methylated… read more here.
Keywords: cancer; detection; methylation analysis; crc ... See more keywords
Transfer of blocker-based qPCR reactions for DNA methylation analysis into a microfluidic LoC system using thermal modeling.
Sign Up to like & getrecommendations! Published in 2022 at "Biomicrofluidics"
DOI: 10.1063/5.0108374
Abstract: Changes in the DNA methylation landscape are associated with many diseases like cancer. Therefore, DNA methylation analysis is of great interest for molecular diagnostics and can be applied, e.g., for minimally invasive diagnostics in liquid… read more here.
Keywords: loc; methylation; loc system; methylation analysis ... See more keywords
Comprehensive benchmarking of software for mapping whole genome bisulfite data: from read alignment to DNA methylation analysis
Sign Up to like & getrecommendations! Published in 2021 at "Briefings in Bioinformatics"
DOI: 10.1093/bib/bbab021
Abstract: Abstract Whole genome bisulfite sequencing is currently at the forefront of epigenetic analysis, facilitating the nucleotide-level resolution of 5-methylcytosine (5mC) on a genome-wide scale. Specialized software have been developed to accommodate the unique difficulties in… read more here.
Keywords: genome bisulfite; methylation; whole genome; analysis ... See more keywords
The complexity in DNA methylation analysis of allergic diseases
Sign Up to like & getrecommendations! Published in 2023 at "Current Opinion in Allergy and Clinical Immunology"
DOI: 10.1097/aci.0000000000000895
Abstract: Purpose of review This review aims to report all the recent studies that are implicated in DNA methylation analysis in the field of allergy and to underline the complexity of the study methodologies and results.… read more here.
Keywords: methylation; dna methylation; allergic diseases; methylation analysis ... See more keywords
Age prediction by methylation analysis of small amounts of DNA using locked nucleic acids
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Forensic Sciences"
DOI: 10.1111/1556-4029.15144
Abstract: Age prediction based on methylation analysis has been reported in many populations, with 10 ng or more of DNA usually required for each determination. In this study, we designed thermostable locked nucleic acid (LNA) primers… read more here.
Keywords: methylation; dna; methylation analysis; analysis ... See more keywords
Genome-wide DNA methylation analysis in pediatric acute myeloid leukemia
Sign Up to like & getrecommendations! Published in 2022 at "Blood Advances"
DOI: 10.1182/bloodadvances.2021005381
Abstract: Key Points FLT3-ITD and high PRDM16 expression induced methylation changes at STAT5 and AP-1 binding sites in pediatric AML. Hypomethylated regions in PRDM16-highly expressed AMLs were correlated with enhanced chromatin accessibilities at multiple genomic regions. read more here.
Keywords: methylation; methylation analysis; genome wide; dna methylation ... See more keywords
Methylation analysis for postpartum depression: a case control study
Sign Up to like & getrecommendations! Published in 2019 at "BMC Psychiatry"
DOI: 10.1186/s12888-019-2172-x
Abstract: BackgroundPostpartum depression (PPD) is a major depressive disorder that occurs after childbirth. Objective diagnostic and predictive methods for PPD are important for early detection and appropriate intervention. DNA methylation has been recognized as a potential… read more here.
Keywords: depression; methylation; analysis; postpartum ... See more keywords
DNA methylation analysis reveals epimutation hotspots in patients with dilated cardiomyopathy-associated laminopathies
Sign Up to like & getrecommendations! Published in 2021 at "Clinical Epigenetics"
DOI: 10.1186/s13148-021-01127-0
Abstract: Background Mutations in LMNA , encoding lamin A/C, lead to a variety of diseases known as laminopathies including dilated cardiomyopathy (DCM) and skeletal abnormalities. Though previous studies have investigated the dysregulation of gene expression in… read more here.
Keywords: analysis reveals; methylation; epimutation hotspots; dilated cardiomyopathy ... See more keywords
Methylation analysis and HPV genotyping of self-collected cervical samples from women not responding to screening invitation and review of the literature
Sign Up to like & getrecommendations! Published in 2017 at "PLoS ONE"
DOI: 10.1371/journal.pone.0172226
Abstract: Aim of the study To assess the feasibility of partial HPV genotyping and methylation analysis of CADM1, MAL, and miR124-2 genes as triage tests in assaying self-collected cervical samples positive for high-risk HPV on primary… read more here.
Keywords: methylation; cervical samples; collected cervical; self collected ... See more keywords