Epigenome-wide DNA methylation analysis of myasthenia gravis.
Sign Up to like & getrecommendations! Published in 2023 at "FEBS open bio"
DOI: 10.1002/2211-5463.13656
Abstract: Myasthenia gravis (MG) is a common neuromuscular junction (NMJ) disorder and autoimmune disease mediated by several antibodies. Several studies have shown that genetic factors play an important role in MG pathogenesis. To gain insight into… read more here.
Keywords: methylation; methylation analysis; dna methylation; wide dna ... See more keywords
Comprehensive structural analysis of a set of various branched glucans by standard methylation analysis, 1H NMR spectroscopy, ESI-mass spectrometry, and capillary electrophoresis.
Sign Up to like & getrecommendations! Published in 2020 at "Carbohydrate research"
DOI: 10.1016/j.carres.2020.107933
Abstract: Various (semi)-synthetic non-digestible glucans (NDG) (resistant (malto)dextrin, isomaltooligosaccharide, soluble corn fiber, polydextrose) were analyzed by methylation analysis, 1H NMR spectroscopy, ESI-MSn, TLC, and capillary electrophoresis (CE/UV). Partly complementary and partly corroborative results were obtained by… read more here.
Keywords: analysis; nmr spectroscopy; electrophoresis; spectroscopy ... See more keywords
Detection of colorectal cancer in urine using DNA methylation analysis
Sign Up to like & getrecommendations! Published in 2021 at "Scientific Reports"
DOI: 10.1038/s41598-021-81900-6
Abstract: Colorectal cancer (CRC) is the second leading cause for cancer-related death globally. Clinically, there is an urgent need for non-invasive CRC detection. This study assessed the feasibility of CRC detection by analysis of tumor-derived methylated… read more here.
Keywords: cancer; detection; methylation analysis; crc ... See more keywords
Transfer of blocker-based qPCR reactions for DNA methylation analysis into a microfluidic LoC system using thermal modeling.
Sign Up to like & getrecommendations! Published in 2022 at "Biomicrofluidics"
DOI: 10.1063/5.0108374
Abstract: Changes in the DNA methylation landscape are associated with many diseases like cancer. Therefore, DNA methylation analysis is of great interest for molecular diagnostics and can be applied, e.g., for minimally invasive diagnostics in liquid… read more here.
Keywords: loc; methylation; loc system; methylation analysis ... See more keywords
Comprehensive benchmarking of software for mapping whole genome bisulfite data: from read alignment to DNA methylation analysis
Sign Up to like & getrecommendations! Published in 2021 at "Briefings in Bioinformatics"
DOI: 10.1093/bib/bbab021
Abstract: Abstract Whole genome bisulfite sequencing is currently at the forefront of epigenetic analysis, facilitating the nucleotide-level resolution of 5-methylcytosine (5mC) on a genome-wide scale. Specialized software have been developed to accommodate the unique difficulties in… read more here.
Keywords: genome bisulfite; methylation; whole genome; analysis ... See more keywords
AutoMethyc: an automated methylation analysis for massively parallel sequencing data
Sign Up to like & getrecommendations! Published in 2025 at "Briefings in Bioinformatics"
DOI: 10.1093/bib/bbaf416
Abstract: Abstract Motivation Bisulfite sequencing (BS-Seq) enables a comprehensive and detailed analysis of DNA methylation patterns at single-nucleotide resolution. While methylation differences can contribute to various diseases, their sincronous occurrence at distinct loci complicates understanding. Therefore,… read more here.
Keywords: methylation; automethyc automated; analysis; automated methylation ... See more keywords
The complexity in DNA methylation analysis of allergic diseases
Sign Up to like & getrecommendations! Published in 2023 at "Current Opinion in Allergy and Clinical Immunology"
DOI: 10.1097/aci.0000000000000895
Abstract: Purpose of review This review aims to report all the recent studies that are implicated in DNA methylation analysis in the field of allergy and to underline the complexity of the study methodologies and results.… read more here.
Keywords: methylation; dna methylation; allergic diseases; methylation analysis ... See more keywords
Age prediction by methylation analysis of small amounts of DNA using locked nucleic acids
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Forensic Sciences"
DOI: 10.1111/1556-4029.15144
Abstract: Age prediction based on methylation analysis has been reported in many populations, with 10 ng or more of DNA usually required for each determination. In this study, we designed thermostable locked nucleic acid (LNA) primers… read more here.
Keywords: methylation; dna; methylation analysis; analysis ... See more keywords
Methylation analysis as a diagnostic tool for sweat gland tumours classification with emphasis on the distinction between digital papillary adenocarcinoma and mimickers
Sign Up to like & getrecommendations! Published in 2025 at "Histopathology"
DOI: 10.1111/his.15479
Abstract: Digital papillary adenocarcinoma (DPA) is a rare sweat gland carcinoma arising on acral sites. The main differential diagnosis included tubular adenoma, hidradenoma, poroid hidradenoma, and mixed tumours, distinction between DPA and these mimickers being crucial… read more here.
Keywords: distinction; classification; sweat gland; methylation analysis ... See more keywords
Abstract 5900: Tumor-independent cfDNA methylation analysis for cancer monitoring during total neoadjuvant treatment in rectal cancer patients
Sign Up to like & getrecommendations! Published in 2025 at "Cancer Research"
DOI: 10.1158/1538-7445.am2025-5900
Abstract: Total neoadjuvant therapy (TNT) is the standard curative-intent treatment for locally advanced rectal cancer (LARC), where patients receive all of their chemotherapy and radiation therapy before surgery. However, monitoring treatment response during TNT can be… read more here.
Keywords: cancer; treatment; treatment response; rectal cancer ... See more keywords
Genome-wide DNA methylation analysis in pediatric acute myeloid leukemia
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DOI: 10.1182/bloodadvances.2021005381
Abstract: Key Points FLT3-ITD and high PRDM16 expression induced methylation changes at STAT5 and AP-1 binding sites in pediatric AML. Hypomethylated regions in PRDM16-highly expressed AMLs were correlated with enhanced chromatin accessibilities at multiple genomic regions. read more here.
Keywords: methylation; methylation analysis; genome wide; dna methylation ... See more keywords