Combined effect of polymorphisms of MTHFR and MTR and arsenic methylation capacity on developmental delay in preschool children in Taiwan
Sign Up to like & getrecommendations! Published in 2020 at "Archives of Toxicology"
DOI: 10.1007/s00204-020-02745-y
Abstract: Polymorphisms of methylenetetrahydrofolate reductase (MTHFR) and methionine synthase (MTR) are related to cognitive dysfunction and mental disability. These genes, along with folate and vitamin B12 levels, are regulators of one-carbon metabolism, which synthesizes S-adenosylmethionine (SAM)… read more here.
Keywords: developmental delay; arsenic methylation; methylation capacity; delay ... See more keywords
Effect of renal impairment on arsenic accumulation, methylation capacity, and safety in acute promyelocytic leukemia (APL) patients treated with arsenic trioxide
Sign Up to like & getrecommendations! Published in 2021 at "Expert Review of Clinical Pharmacology"
DOI: 10.1080/17512433.2021.1938549
Abstract: ABSTRACT Background: Arsenic trioxide (ATO) was successfully applied to treat acute promyelocytic leukemia (APL). Methods: Inorganic arsenic (iAs), monomethylarsonic acid (MMAV) and dimethyarsinic acid (DMAV) in plasma of 143 APL patients with different renal function… read more here.
Keywords: apl patients; methylation capacity; arsenic accumulation; renal impairment ... See more keywords