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Published in 2020 at "Theriogenology"
DOI: 10.1016/j.theriogenology.2020.07.008
Abstract: DNA methylation is a crucial element in the epigenetic regulation of mammalian embryonic development. However, the subtle changes in DNA methylation differ in species, and, little information is known regarding the dynamics of DNA methylation…
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Keywords:
methylation;
genome activation;
zygotic genome;
methylation dynamics ... See more keywords
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Published in 2019 at "Essays in biochemistry"
DOI: 10.1042/ebc20190039
Abstract: Transposable elements dominate the mammalian genome, but their contribution to genetic and epigenetic regulation has been largely overlooked. This was in part due to technical limitations, which made the study of repetitive sequences at single…
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Keywords:
methylation;
transposable element;
methylation dynamics;
transposable elements ... See more keywords
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Published in 2022 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2022.909424
Abstract: The molecular mechanisms that regulate stem cell pluripotency and differentiation has shown the crucial role that methylation plays in this process. DNA methylation has been shown to be important in the context of developmental pathways,…
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Keywords:
methylation;
cancer stem;
methylation dynamics;
stem cells ... See more keywords
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Published in 2017 at "Genes"
DOI: 10.3390/genes8050138
Abstract: Cytosine modifications, including DNA methylation, are stable epigenetic marks that may translate environmental change into transcriptional regulation. Research has begun to investigate DNA methylation dynamics in relation to cocaine use disorders. Specifically, DNA methylation machinery,…
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Keywords:
methylation;
methylation dynamics;
cocaine brain;
dna methylation ... See more keywords