Increasing Specificity of Targeted DNA Methylation Editing by Non-Enzymatic CRISPR/dCas9-Based Steric Hindrance
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DOI: 10.3390/biomedicines11051238
Abstract: As advances in genome engineering inch the technology towards wider clinical use—slowed by technical and ethical hurdles—a newer offshoot, termed “epigenome engineering”, offers the ability to correct disease-causing changes in the DNA without changing its… read more here.
Keywords: methylation editing; increasing specificity; dna methylation; targeted dna ... See more keywords