Loss of N1-methylation of G37 in tRNA induces ribosome stalling and reprograms gene expression
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DOI: 10.7554/elife.70619
Abstract: N1-methylation of G37 is required for a subset of tRNAs to maintain the translational reading-frame. While loss of m1G37 increases ribosomal +1 frameshifting, whether it incurs additional translational defects is unknown. Here, we address this… read more here.
Keywords: m1g37 deficiency; methylation g37; ribosome stalling; deficiency ... See more keywords