DNA methylation inhibitors: Retrospective and perspective view.
Sign Up to like & getrecommendations! Published in 2021 at "Advances in cancer research"
DOI: 10.1016/bs.acr.2021.03.007
Abstract: DNA methylation is an epigenetic modification that contributes to essential biological processes such as retrotransposon silencing, cell differentiation, genomic imprinting and X-chromosome inactivation. DNA methylation generates a stable epigenetic mark associated with silencing of gene… read more here.
Keywords: inhibitors retrospective; methylation inhibitors; dna; dna methylation ... See more keywords
A New Molecular Mechanism Underlying the Antitumor Effect of DNA Methylation Inhibitors via an Antiviral Immune Response.
Sign Up to like & getrecommendations! Published in 2017 at "Advances in protein chemistry and structural biology"
DOI: 10.1016/bs.apcsb.2016.08.005
Abstract: Chromatin remodeling mediated by DNA methylation and histone modifications play critical roles in the transcriptional regulation of protein-coding genes, noncoding RNAs such as microRNAs, and endogenous retroviruses (ERVs). Many studies have shown that aberrant DNA… read more here.
Keywords: effect dna; methylation; dna methylation; methylation inhibitors ... See more keywords