Renal cell carcinoma: predicting RUNX3 methylation level and its consequences on survival with CT features
Sign Up to like & getrecommendations! Published in 2019 at "European Radiology"
DOI: 10.1007/s00330-019-06049-3
Abstract: PurposeTo investigate associations between CT imaging features, RUNX3 methylation level, and survival in clear cell renal cell carcinoma (ccRCC).Materials and methodsPatients were divided into high RUNX3 methylation and low RUNX3 methylation groups according to RUNX3… read more here.
Keywords: runx3 methylation; methylation; cell; methylation level ... See more keywords
LINE-1 retrotransposon methylation in chorionic villi of first trimester miscarriages with aneuploidy
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Assisted Reproduction and Genetics"
DOI: 10.1007/s10815-020-02003-1
Abstract: Purpose High frequency of aneuploidy in meiosis and cleavage stage coincides with waves of epigenetic genome reprogramming that may indicate a possible association between epigenetic mechanisms and aneuploidy occurrence. This study aimed to assess the… read more here.
Keywords: methylation; chorionic villi; line; methylation level ... See more keywords
Differentially methylation of IFI44L gene promoter in Iranian patients with systemic lupus erythematosus and rheumatoid arthritis.
Sign Up to like & getrecommendations! Published in 2022 at "Molecular biology reports"
DOI: 10.1007/s11033-022-07134-5
Abstract: BACKGROUND Systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA) are multisystemic autoimmune diseases with multifactorial nature. Considering the limitations of the current conventional serological tests for the diagnosis of these diseases, researchers strive to find more new valid… read more here.
Keywords: methylation level; methylation; systemic lupus; promoter ... See more keywords
Defining a prognostic score based on O6-methylguanine-DNA methyltransferase cut-off methylation level determined by pyrosequencing in patients with glioblastoma multiforme
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Neuro-Oncology"
DOI: 10.1007/s11060-018-2981-7
Abstract: PurposeEpigenetic variations in the O6-methylguanine-methyltransferase gene had been widely associated with a favorable impact on survival in patients affected by glioblastoma multiforme (GBM). Aim of this study is to explore a scoring system based on… read more here.
Keywords: methylation; determined pyrosequencing; methylation level; glioblastoma multiforme ... See more keywords
The DNA methylation level is associated with the superior growth of the hybrid crosses in the Pacific oyster Crassostrea gigas
Sign Up to like & getrecommendations! Published in 2022 at "Aquaculture"
DOI: 10.1016/j.aquaculture.2021.737421
Abstract: Abstract Pacific oyster Crassostrea gigas is one of the most important global aquaculture bivalve species, and its growth traits have been improved by heterosis in the progeny produced by hybridization. However, comprehension of the molecular… read more here.
Keywords: methylation; growth; methylation level; heterosis ... See more keywords
rs9939609 FTO genotype associations with FTO methylation level influences body mass and telomere length in an Australian rural population
Sign Up to like & getrecommendations! Published in 2017 at "International Journal of Obesity"
DOI: 10.1038/ijo.2017.127
Abstract: Background:The fat mass- and obesity-associated (FTO) gene influences energy homeostasis in humans. Although the obesity-related variant, rs9939609 has been replicated across a number of cohort studies, there remains significant variance and a low to modest… read more here.
Keywords: methylation; telomere length; methylation level; fto methylation ... See more keywords
Correlation between global methylation level of peripheral blood leukocytes and serum C reactive protein level modified by MTHFR polymorphism: a cross-sectional study
Sign Up to like & getrecommendations! Published in 2018 at "BMC Cancer"
DOI: 10.1186/s12885-018-4089-z
Abstract: BackgroundChronic inflammatory conditions are associated with higher tumor incidence through epigenetic and genetic alterations. Here, we focused on an association between an inflammation marker, C-reactive-protein (CRP), and global DNA methylation levels of peripheral blood leukocytes.MethodsThe… read more here.
Keywords: methylation; blood leukocytes; methylation level; level ... See more keywords
Methylation-level inferences and detection of differential methylation with MeDIP-seq data
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DOI: 10.1371/journal.pone.0201586
Abstract: DNA methylation is an essential epigenetic modification involved in regulating the expression of mammalian genomes. A variety of experimental approaches to generate genome-wide or whole-genome DNA methylation data have emerged in recent years. Methylated DNA… read more here.
Keywords: methylation; whole genome; methylation level; medip seq ... See more keywords
Changes in DNA methylation during epigenetic-associated sex reversal under low temperature in Takifugu rubripes
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DOI: 10.1371/journal.pone.0221641
Abstract: DNA methylation has frequently been implicated in sex determination and differentiation in teleost species. In order to detect the DNA methylation patterns established during sexual differentiation in tiger pufferfish T. rubripes, we performed comprehensive whole… read more here.
Keywords: methylation; male; methylation level; sex ... See more keywords
Association of LBX1 Gene Methylation Level with Disease Severity in Patients with Idiopathic Scoliosis: Study on Deep Paravertebral Muscles
Sign Up to like & getrecommendations! Published in 2022 at "Genes"
DOI: 10.3390/genes13091556
Abstract: Idiopathic scoliosis (IS) is a multifactorial disease with a genetic background. The association of Ladybird Homeobox 1 (LBX1) polymorphisms with IS has been proven in multiple studies. However, the epigenetic mechanisms have not been evaluated.… read more here.
Keywords: methylation; methylation level; deep paravertebral; association ... See more keywords