Articles with "methylation modification" as a keyword



Latest Progress on RNA Methylation Modification in Hepatocellular Carcinoma

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Published in 2020 at "Cancer"

DOI: 10.18063/c+.v2i2.292

Abstract: Hepatocellular carcinoma (HCC) is the most common malignant tumor worldwide, characterized by insidious onset as well as high incidence, recurrence, metastasis, and mortality rates. At present, there is no effective clinical treatment method except transplantation.… read more here.

Keywords: methylation modification; rna methylation; hepatocellular carcinoma;

MiR-205 Regulates LRRK2 Expression in Dopamine Neurons in Parkinson’s Disease through Methylation Modification

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Published in 2022 at "Iranian Journal of Public Health"

DOI: 10.18502/ijph.v51i7.10098

Abstract: Background: We explored the methylation modification in miR-205 promoter during the pathological changes of Parkinson’s disease (PD) and its regulation on Leucine-Rich Repeat Kinase 2 (LRRK2), clarified the important role of methylation in miR-205 promoter… read more here.

Keywords: methylation modification; methylation; mir 205; region ... See more keywords
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Histone Lysine Methylation Modification and Its Role in Vascular Calcification

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Published in 2022 at "Frontiers in Endocrinology"

DOI: 10.3389/fendo.2022.863708

Abstract: Histone methylation is an epigenetic change mediated by histone methyltransferase, and has been connected to the beginning and progression of several diseases. The most common ailments that affect the elderly are cardiovascular and cerebrovascular disorders.… read more here.

Keywords: methylation modification; methylation; histone; role ... See more keywords
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Expression pattern and clinical value of Key RNA methylation modification regulators in ischemic stroke

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Published in 2022 at "Frontiers in Genetics"

DOI: 10.3389/fgene.2022.1009145

Abstract: Ischemic stroke (IS) is one of the major causes of death and disability worldwide, and effective diagnosis and treatment methods are lacking. RNA methylation, a common epigenetic modification, plays an important role in disease progression.… read more here.

Keywords: methylation modification; methylation; rna methylation; expression ... See more keywords
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Comprehensive analysis of m6A RNA methylation modification patterns and the immune microenvironment in osteoarthritis

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Published in 2023 at "Frontiers in Immunology"

DOI: 10.3389/fimmu.2023.1128459

Abstract: Background Osteoarthritis (OA) is the most common joint degenerative disease, and so far, there is no effective therapy to prevent or delay its development. Considerable attention is now being given to the impact of m6A… read more here.

Keywords: m6a rna; methylation modification; modification; rna methylation ... See more keywords