Long-term daily temozolomide with dose-dependent efficacy in MGMT promotor methylation negative recurrent high-grade astrocytoma
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DOI: 10.1007/s00280-017-3415-5
Abstract: Temozolomide (TMZ) for malignant gliomas is traditionally dosed in 5 out of a 28-day cycle, however alternative regimens exist, including dose-dense. Continuous daily dosing is available, but the acceptable dose and duration of therapy is… read more here.
Keywords: mgmt promotor; methylation negative; long term; promotor methylation ... See more keywords