Methylation pattern of polymorphically imprinted nc886 is not conserved across mammalia
Sign Up to like & getrecommendations! Published in 2022 at "PLoS ONE"
DOI: 10.1101/2021.12.03.471165
Abstract: Background In humans, the nc886 locus is a polymorphically imprinted metastable epiallele. Periconceptional conditions have an effect on the methylation status of nc886, and further, this methylation status is associated with health outcomes in later… read more here.
Keywords: polymorphically imprinted; methylation; dna methylation; guinea pigs ... See more keywords
A convolutional neural network-based regression model to infer the epigenetic crosstalk responsible for CG methylation patterns
Sign Up to like & getrecommendations! Published in 2021 at "BMC Bioinformatics"
DOI: 10.1186/s12859-021-04272-8
Abstract: Background Epigenetic modifications, including CG methylation (a major form of DNA methylation) and histone modifications, interact with each other to shape their genomic distribution patterns. However, the entire picture of the epigenetic crosstalk regulating the… read more here.
Keywords: methylation; epigenetic crosstalk; model; methylation patterns ... See more keywords
Altered methylation pattern of the SRD5A2 gene in the cerebrospinal fluid of post-finasteride patients: a pilot study
Sign Up to like & getrecommendations! Published in 2019 at "Endocrine Connections"
DOI: 10.1530/ec-19-0199
Abstract: Context Post-finasteride syndrome (PFS) occurs in patients with androgenic alopecia after suspension of the finasteride treatment, leading to a large variety of persistent side effects. Despite the severity of the clinical picture, the mechanism underlying… read more here.
Keywords: methylation; finasteride; methylation pattern; pfs patients ... See more keywords
The Methylation Pattern for Knee and Hip Osteoarthritis
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2020.602024
Abstract: Osteoarthritis is one of the most prevalent chronic joint diseases for middle-aged and elderly people. But in recent years, the number of young people suffering from the disease increases quickly. It is known that osteoarthritis… read more here.
Keywords: methylation; hip; knee hip; osteoarthritis ... See more keywords