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Published in 2022 at "Birth Defects Research"
DOI: 10.1002/bdr2.2090
Abstract: Environmental factors may influence the development of tetralogy of Fallot (TOF), and DNA methylation patterns may reveal specific chemical signatures of perturbations during cardiac development. We investigated whether blood and buccal cells could be viable…
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Keywords:
dna methylation;
tetralogy fallot;
methylation patterns;
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Published in 2019 at "Cancer Medicine"
DOI: 10.1002/cam4.1930
Abstract: Hepatocellular carcinoma (HCC) is a malignancy with poor prognosis. Complex genetic and epigenetic alterations are the two primary causes of HCC. The aim of the study was mainly to explore the correlation between the methylation…
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Keywords:
hepatocellular carcinoma;
carcinoma;
association methylation;
methylation patterns ... See more keywords
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Published in 2017 at "STEM CELLS"
DOI: 10.1002/stem.2563
Abstract: Early embryonic stages of pluripotency are modeled for epigenomic studies primarily with human embryonic stem cells (ESC) or induced pluripotent stem cells (iPSCs). For analysis of DNA methylation however, ESCs and iPSCs do not accurately…
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Keywords:
stem cells;
methylation;
dental pulp;
methylation patterns ... See more keywords
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Published in 2019 at "Animal reproduction science"
DOI: 10.1016/j.anireprosci.2019.106124
Abstract: Uterine receptivity for the embryo is established and maintained through a series of precise cellular and molecular events, such as DNA methylation. There have been no studies to elucidate entire genome DNA methylation changes associated…
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Keywords:
genome wide;
methylation;
wide dna;
methylation patterns ... See more keywords
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Published in 2020 at "Biochimie"
DOI: 10.1016/j.biochi.2020.07.004
Abstract: Epigenetic modifications govern gene expression by guiding the human genome on 'what to express and what not to'. DNA methyltransferases (DNMTs) establish methylation patterns on DNA, particularly in CpG islands, and such patterns play a…
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Keywords:
methylation;
novo methyltransferases;
potential players;
methyltransferases potential ... See more keywords
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Published in 2020 at "Insect biochemistry and molecular biology"
DOI: 10.1016/j.ibmb.2020.103370
Abstract: DNA methylation is an important epigenetic modification that is prone to stochastic variation and is responsive to environmental factors. Yet changes in DNA methylation could persist across generations and thus play an important role in…
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Keywords:
chloridea virescens;
methylation;
dna methylation;
methylation patterns ... See more keywords
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Published in 2021 at "Neurobiology of aging"
DOI: 10.1016/j.neurobiolaging.2021.08.006
Abstract: DNA methylation is a well-characterized epigenetic modification involved in numerous molecular and cellular functions. Methylation patterns have also been associated with aging mechanisms. However, how DNA methylation patterns change within key brain regions involved in…
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Keywords:
methylation;
hippocampus;
age;
methylation patterns ... See more keywords
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Published in 2017 at "Reproductive biology"
DOI: 10.1016/j.repbio.2017.05.010
Abstract: Infertility affects about 15% of couples worldwide, with approximately 7% of males suffering from infertility problems. This study was designed to assess the relationship between alterations in sperm DNA methylation patterns and semen parameters in…
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Keywords:
methylation;
sperm dna;
semen parameters;
subfertile males ... See more keywords
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Published in 2018 at "Research in veterinary science"
DOI: 10.1016/j.rvsc.2018.07.006
Abstract: Genetic and epigenetic alterations in the equine sarcoid, a locally invasive skin tumour of equids, are still poorly characterized. Numerous studies have provided reliable evidence for the relationship between the development of cancer and the…
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Keywords:
methylation;
s100a14 pou2f3;
equine sarcoid;
methylation patterns ... See more keywords
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Published in 2021 at "Genomics"
DOI: 10.1016/j.ygeno.2021.11.007
Abstract: Transposable elements (TEs) exhibit vast diversity across insect orders and are one of the major factors driving insect evolution and speciation. Presence of TEs can be both beneficial and deleterious to their host. While it…
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Keywords:
methylation;
patterns tf2;
stress;
tf2 retrotransposons ... See more keywords
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Published in 2022 at "Nature Communications"
DOI: 10.1038/s41467-021-27690-x
Abstract: DNA methylation shapes the epigenetic landscape of the genome, plays critical roles in regulating gene expression, and ensures transposon silencing. As is evidenced by the numerous defects associated with aberrant DNA methylation landscapes, establishing proper…
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Keywords:
methylation patterns;
dna methylation;
methylation;
tissue specific ... See more keywords