Articles with "methylation profile" as a keyword



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DNA methylation profile in patients with indolent systemic mastocytosis

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Published in 2021 at "Clinical and Translational Allergy"

DOI: 10.1002/clt2.12074

Abstract: Abstract Background Mastocytosis is a clinically heterogeneous, usually acquired disease of the mast cells with a survival time that depends on the onset of the disease and ranges from skin‐limited to systemic disease, including indolent… read more here.

Keywords: methylation; methylation profile; kit; dna methylation ... See more keywords
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DNA methylation profile in the whole blood of acute coronary syndrome patients with aspirin resistance

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Published in 2022 at "Journal of Clinical Laboratory Analysis"

DOI: 10.1002/jcla.24821

Abstract: Aspirin resistance (AR) results in major adverse cardiovascular events, and DNA methylation might participate in the regulation of this pathological process. read more here.

Keywords: profile whole; aspirin resistance; dna methylation; methylation profile ... See more keywords
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Evaluation of genome-wide DNA methylation profile of human embryos with different developmental competences.

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Published in 2021 at "Human reproduction"

DOI: 10.1093/humrep/deab074

Abstract: STUDY QUESTION Do embryos with different developmental competence exhibit different DNA methylation profiles at the blastocyst stage? SUMMARY ANSWER We established genome-wide DNA methylome analysis for embryo trophectoderm (TE) biopsy samples and our findings demonstrated… read more here.

Keywords: genome wide; methylation; methylation profile; wide dna ... See more keywords
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P–522 Cervical secretion methylation profile is associated with the success of frozen-thawed embryo transfer - a proof-of-concept study

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Published in 2021 at "Human Reproduction"

DOI: 10.1093/humrep/deab130.521

Abstract: Is cervical secretion gene methylation profile different between receptive and non-receptive endometrium and associated with implantation outcome in frozen-embryo transfer (FET) cycle? The combination of candidate genes methylation profiles obtained from cervical secretion showed significant… read more here.

Keywords: methylation; methylation profile; study; implantation ... See more keywords
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The lung DNA methylation profile of patients with COPD: relationship with smoking and airflow limitation severity.

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Published in 2020 at "ERJ Open Research"

DOI: 10.1183/23120541.lsc-2020.48

Abstract: Background: Tobacco smoking is the main environmental risk factor for COPD. Smoking exposure alters DNA methylation, which in turn regulates gene transcription. Yet, not all smokers develop COPD. This study sought to get further insight… read more here.

Keywords: methylation; methylation profile; smoking; copd ... See more keywords
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The DNA methylation profile of non-coding RNAs improves prognosis prediction for pancreatic adenocarcinoma

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Published in 2019 at "Cancer Cell International"

DOI: 10.1186/s12935-019-0828-8

Abstract: BackgroundCompelling lines of evidence indicate that DNA methylation of non-coding RNAs (ncRNAs) plays critical roles in various tumour progression. In addition, the differential methylation of ncRNAs can predict prognosis of patients. However, little is known… read more here.

Keywords: methylation; cpg sites; prognosis; methylation profile ... See more keywords
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An Integrative Analysis of DNA Methylation Pattern in Myotonic Dystrophy Type 1 Samples Reveals a Distinct DNA Methylation Profile between Tissues and a Novel Muscle-Associated Epigenetic Dysregulation

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Published in 2022 at "Biomedicines"

DOI: 10.3390/biomedicines10061372

Abstract: Myotonic dystrophy type 1 (DM1) is a progressive, non-treatable, multi-systemic disorder. To investigate the contribution of epigenetics to the complexity of DM1, we compared DNA methylation profiles of four annotated CpG islands (CpGis) in the… read more here.

Keywords: methylation; dna methylation; muscle; methylation profile ... See more keywords
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Next-Generation Sequencing Analysis of CpG Methylation of a Tumor Suppressor Gene SHP-1 Promoter in Stable Cell Lines and HCV-Positive Patients

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Published in 2022 at "Viruses"

DOI: 10.3390/v14112352

Abstract: Hepatitis C virus (HCV) is the major causative pathogen associated with hepatocellular carcinoma and liver cirrhosis. The main virion component, the Core (C) protein, is involved in multiple aspects of HCV pathology including oncogenesis and… read more here.

Keywords: cpg methylation; methylation; next generation; methylation profile ... See more keywords

DNA methylation profile of the DKK2 gene as a biomarker in patients with colorectal cancer

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Published in 2017 at "Genetics and Molecular Research"

DOI: 10.4238/gmr16039816

Abstract: Purpose: Epigenetic changes can be detected in precancerous lesions, suggesting that may be involved in the early stages of carcinogenesis. The methylation of specifics genes has been correlated with the outcome of many different types… read more here.

Keywords: methylation; dkk2 gene; methylation profile; cancer ... See more keywords