Articles with "methylation signature" as a keyword



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A 10-gene prognostic methylation signature for stage I–III cervical cancer

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Published in 2020 at "Archives of Gynecology and Obstetrics"

DOI: 10.1007/s00404-020-05524-3

Abstract: Purpose Cervical cancer (CC) patients usually have poor prognosis. The present study aims to find a DNA methylation signature for predicting survival of CC patients. Methods We selected CC patients at pathological stage I–III with… read more here.

Keywords: methylation; model; cancer; gene ... See more keywords
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Identification of a New m6A Regulator-Related Methylation Signature for Predicting the Prognosis and Immune Microenvironment of Patients with Pancreatic Cancer

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Published in 2023 at "Mediators of Inflammation"

DOI: 10.1155/2023/5565054

Abstract: Pancreatic cancer (PC) is a malignant tumor of the digestive system that has a bad prognosis. N6-methyladenosine (m6A) is involved in a wide variety of biological activities due to the fact that it is the… read more here.

Keywords: methylation; methylation signature; prognosis; gene methylation ... See more keywords
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Development and validation of an integrative methylation signature and nomogram for predicting survival in clear cell renal cell carcinoma.

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Published in 2020 at "Translational andrology and urology"

DOI: 10.21037/tau-19-853

Abstract: Background Growing evidence has shown that genetic or epigenetic alterations are highly involved in the initiation and progression of renal cell carcinoma (RCC). This study aimed to find prognostic methylation markers in clear cell RCC… read more here.

Keywords: methylation; analysis; signature; cell ... See more keywords
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HPV Infection Leaves a DNA Methylation Signature in Oropharyngeal Cancer Affecting Both Coding Genes and Transposable Elements

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Published in 2021 at "Cancers"

DOI: 10.3390/cancers13143621

Abstract: Simple Summary The HPV oncoproteins E6 and E7 can modulate the expression and activity of the maintenance DNA methyltransferase 1, suggesting that HPV carcinogenic mechanisms may include aberrant DNA methylation. Some studies previously proposed both… read more here.

Keywords: methylation; expression; hpv; dna methylation ... See more keywords
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Characterization of a prognostic four-gene methylation signature associated with radiotherapy for head and neck squamous cell carcinoma

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Published in 2019 at "Molecular Medicine Reports"

DOI: 10.3892/mmr.2019.10294

Abstract: Head and neck squamous cell carcinoma (HNSCC) remains one of the most common malignancies associated with poor prognosis. DNA methylation has emerged as an important mechanism underlying the radio-resistance of tumors. Prognostic biomarkers based on… read more here.

Keywords: methylation; gene methylation; gene; methylation signature ... See more keywords