Protein methylome analysis in Arabidopsis reveals regulation in RNA-related processes.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of proteomics"
DOI: 10.1016/j.jprot.2019.103601
Abstract: Protein methylation has been proposed as an important post-translational modification, which occurs predominantly on lysine and arginine residues. Recent discoveries have revealed that protein methylation is also present on non-histones besides histones, and plays critical… read more here.
Keywords: methylation sites; methylation; analysis; protein methylation ... See more keywords
iRNA-PseKNC(2methyl): Identify RNA 2'-O-methylation sites by convolution neural network and Chou's pseudo components.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of theoretical biology"
DOI: 10.1016/j.jtbi.2018.12.034
Abstract: The 2'-O-methylation transferase is involved in the process of 2'-O-methylation. In catalytic processes, the 2-hydroxy group of the ribose moiety of a nucleotide accept a methyl group. This methylation process is a post-transcriptional modification, which… read more here.
Keywords: methylation sites; methylation; convolution neural; pseknc 2methyl ... See more keywords
Multifactorial feature extraction and site prognosis model for protein methylation data.
Sign Up to like & getrecommendations! Published in 2022 at "Briefings in functional genomics"
DOI: 10.1093/bfgp/elac034
Abstract: Integrated studies (multi-omics studies) comprising genetic, proteomic and epigenetic data analyses have become an emerging topic in biomedical research. Protein methylation is a posttranslational modification that plays an essential role in various cellular activities. The… read more here.
Keywords: methylation; methylation sites; protein methylation; methylation data ... See more keywords
DNA methylation patterns–based subtype distinction and identification of soft tissue sarcoma prognosis
Sign Up to like & getrecommendations! Published in 2021 at "Medicine"
DOI: 10.1097/md.0000000000023787
Abstract: Abstract Soft tissue sarcomas (STSs) are heterogeneous at the clinical with a variable tendency of aggressive behavior. In this study, we constructed a specific DNA methylation-based classification to identify the distinct prognosis-subtypes of STSs based… read more here.
Keywords: methylation sites; prognosis; methylation; dna methylation ... See more keywords
Research on the pathological mechanism of rectal adenocarcinoma based on DNA methylation
Sign Up to like & getrecommendations! Published in 2023 at "Medicine"
DOI: 10.1097/md.0000000000032763
Abstract: Colorectal cancer is one of the 3 most common cancers worldwide. In this study, a weighted network-based analysis method was proposed to explore the pathological mechanisms and prognostic targets of rectal adenocarcinoma (READ) at the… read more here.
Keywords: methylation; methylation sites; dna methylation; rectal adenocarcinoma ... See more keywords
Fast Prediction of Protein Methylation Sites Using a Sequence-Based Feature Selection Technique
Sign Up to like & getrecommendations! Published in 2019 at "IEEE/ACM Transactions on Computational Biology and Bioinformatics"
DOI: 10.1109/tcbb.2017.2670558
Abstract: Protein methylation, an important post-translational modification, plays crucial roles in many cellular processes. The accurate prediction of protein methylation sites is fundamentally important for revealing the molecular mechanisms undergoing methylation. In recent years, computational prediction… read more here.
Keywords: methylation sites; protein methylation; methylation; sequence ... See more keywords
Arginine methylation sites on SepIVA help balance elongation and septation in Mycobacterium smegmatis
Sign Up to like & getrecommendations! Published in 2022 at "Molecular Microbiology"
DOI: 10.1111/mmi.15006
Abstract: The growth of mycobacterial cells requires successful coordination between elongation and septation. However, it is not clear which factors mediate this coordination. Here, we studied the function and post‐translational modification of an essential division factor,… read more here.
Keywords: methylation sites; elongation septation; elongation; mycobacterium smegmatis ... See more keywords
Identification of Melanoma Subsets Based on DNA Methylation Sites and Construction of a Prognosis Evaluation Model
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Oncology"
DOI: 10.1155/2022/6608650
Abstract: Background Melanoma is a lethal skin malignant tumor, and its formation or development is regulated by various genetic and epigenetic molecules. Although there are traditional methods provided for the doctors to evaluate the patients' prognosis… read more here.
Keywords: methylation; prognosis; melanoma; methylation sites ... See more keywords
DNA methylation molecular subtypes for prognosis prediction in lung adenocarcinoma
Sign Up to like & getrecommendations! Published in 2022 at "BMC Pulmonary Medicine"
DOI: 10.1186/s12890-022-01924-0
Abstract: Aims Lung cancer is one of the main results in tumor-related mortality. Methylation differences reflect critical biological features of the etiology of LUAD and affect prognosis. Methods In the present study, we constructed a prediction… read more here.
Keywords: methylation sites; prognosis; methylation; dna methylation ... See more keywords
DNA methylation data-based molecular subtype classification and prediction in patients with gastric cancer
Sign Up to like & getrecommendations! Published in 2020 at "Cancer Cell International"
DOI: 10.1186/s12935-020-01253-4
Abstract: Background Genetic and epigenetic alterations have been indicated to be closely correlated with the carcinogenesis, DNA methylation is one of most frequently occurring molecular behavior that take place early during this complicated process in gastric… read more here.
Keywords: gastric cancer; methylation sites; methylation; dna methylation ... See more keywords
iMethylK_pseAAC: Improving Accuracy of Lysine Methylation Sites Identification by Incorporating Statistical Moments and Position Relative Features into General PseAAC via Chou’s 5-steps Rule
Sign Up to like & getrecommendations! Published in 2019 at "Current Genomics"
DOI: 10.2174/1389202920666190809095206
Abstract: Background: Methylation is one of the most important post-translational modifications in the human body which usually arises on lysine among the most intensely modified residues. It performs a dynamic role in numerous biological procedures, such… read more here.
Keywords: methylation sites; methylation; lysine methylation; pseaac ... See more keywords