Genome-wide methylation, transcriptome and characteristic metabolites reveal the balance between diosgenin and brassinosteroids in Dioscorea zingiberensis
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DOI: 10.1093/hr/uhae056
Abstract: Abstract Diosgenin (DG) is a bioactive metabolite isolated from Dioscorea species, renowned for its medicinal properties. Brassinosteroids (BRs) are a class of crucial plant steroidal hormones. Cholesterol and campesterol are important intermediates of DG and… read more here.
Keywords: transcriptome characteristic; genome wide; methylation transcriptome; zingiberensis ... See more keywords
The profile of genome-wide DNA methylation, transcriptome, and proteome in streptomycin-resistant Mycobacterium tuberculosis
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DOI: 10.1371/journal.pone.0297477
Abstract: Streptomycin-resistant (SM-resistant) Mycobacterium tuberculosis (M. tuberculosis) is a major concern in tuberculosis (TB) treatment. However, the mechanisms underlying streptomycin resistance remain unclear. This study primarily aimed to perform preliminary screening of genes associated with streptomycin… read more here.
Keywords: analysis; tuberculosis; transcriptome proteome; methylation transcriptome ... See more keywords
Genome-wide DNA methylation and transcriptome sequencing analyses of lens tissue in an age-related mouse cataract model
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DOI: 10.1371/journal.pone.0316766
Abstract: DNA methylation is known to be associated with cataracts. In this study, we used a mouse model and performed DNA methylation and transcriptome sequencing analyses to find epigenetic indicators for age-related cataracts (ARC). Anterior lens… read more here.
Keywords: methylation; genome wide; dna methylation; model ... See more keywords
Preliminary study based on methylation and transcriptome gene sequencing of lncRNAs and immune infiltration in hypopharyngeal carcinoma
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DOI: 10.3389/fonc.2023.1117622
Abstract: Background Hypopharyngeal squamous cell cancer (HSCC) is one of the most malignant tumors of the head and neck. It is not easy to detect in the early stage due to its hidden location; thus, lymph… read more here.
Keywords: infiltration; methylation; cell; methylation transcriptome ... See more keywords