Improvement on Permeability of Cyclic Peptide/Peptidomimetic: Backbone N-Methylation as A Useful Tool
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DOI: 10.3390/md19060311
Abstract: Peptides have a three-dimensional configuration that can adopt particular conformations for binding to proteins, which are well suited to interact with larger contact surface areas on target proteins. However, low cell permeability is a major… read more here.
Keywords: permeability cyclic; methylation; backbone methylation; methylation useful ... See more keywords