Editing of DNA Methylation Using dCas9-Peptide Repeat and scFv-TET1 Catalytic Domain Fusions.
Sign Up to like & getrecommendations! Published in 2018 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-7774-1_23
Abstract: DNA methylation, one of the most studied epigenetic modifications, regulates many biological processes. Dysregulation of DNA methylation is implicated in the etiology of several diseases, such as cancer and imprinting diseases. Accordingly, technologies designed to… read more here.
Keywords: methylation using; editing dna; dna; scfv ... See more keywords
A survey of the approaches for identifying differential methylation using bisulfite sequencing data
Sign Up to like & getrecommendations! Published in 2018 at "Briefings in Bioinformatics"
DOI: 10.1093/bib/bbx013
Abstract: &NA; DNA methylation is an important epigenetic mechanism that plays a crucial role in cellular regulatory systems. Recent advancements in sequencing technologies now enable us to generate highâthroughput methylation data and to measure methylation up… read more here.
Keywords: methylation; methylation using; survey; differential methylation ... See more keywords