Characterization of 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (IspG) from Plasmodium vivax and it's potential as an antimalarial drug target.
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DOI: 10.1016/j.ijbiomac.2016.12.033
Abstract: The prokaryotic type Methyl Erythritol phosphate (MEP) pathway functional in the apicoplast of Plasmodium is indispensable for the erythrocytic stages of the parasite. It is the sole process of isoprenoids biosynthesis in the parasite and… read more here.
Keywords: methylbut diphosphate; hydroxy methylbut; target; diphosphate ... See more keywords