Synthesis and Cytotoxic Evaluation of 3-Methylidenechroman-4-ones
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DOI: 10.3390/molecules24101868
Abstract: In the search for new anticancer agents, a library of variously substituted 3-methylidenechroman-4-ones was synthesized using Horner–Wadsworth–Emmons methodology. Acylation of diethyl methylphosphonate with selected ethyl salicylates furnished 3-diethoxyphosphorylchromen-4-ones which were next used as Michael acceptors… read more here.
Keywords: methodology; methylidenechroman ones; evaluation methylidenechroman; cytotoxic evaluation ... See more keywords