NKX3.1 immunohistochemistry and methylome profiling in mesenchymal chondrosarcoma: additional diagnostic value for a well-defined disease?
Sign Up to like & getrecommendations! Published in 2023 at "Pathology"
DOI: 10.1158/1538-7445.am2023-6218
Abstract: Mesenchymal chondrosarcoma (MCS) is a rare and highly aggressive tumour of soft tissue and bone that is defined by an underlying and highly specific fusion transcript involving HEY1 and NCOA2. Histologically, the tumours show a… read more here.
Keywords: component; mesenchymal chondrosarcoma; diagnostic value; round cell ... See more keywords
Diagnostic DNA methylome profiling and the WHO 5th edition CNS tumor classification.
Sign Up to like & getrecommendations! Published in 2022 at "Clinical neuropathology"
DOI: 10.5414/np301493
Abstract: The long-awaited 5th edition of the WHO brain tumor classification has put considerable emphasis on the importance of diagnostic DNA methylation profiling. In this article, the authors comparatively discuss selected practical aspects as well as… read more here.
Keywords: methylome profiling; diagnostic dna; 5th edition; tumor classification ... See more keywords