Integrative analysis of methylome and transcriptome variation of identified cardiac disease-specific genes in human cardiomyocytes after PM2.5 exposure.
Sign Up to like & getrecommendations! Published in 2018 at "Chemosphere"
DOI: 10.1016/j.chemosphere.2018.09.010
Abstract: PM2.5 exposure is strongly linked to cardiac disease. Subtle epigenetic or transcriptional alterations induced by PM2.5 might contribute to pathogenesis and disease susceptibility of cardiac disease. It is still a major challenge to identify biological… read more here.
Keywords: pm2; methylome transcriptome; ontology; cardiac disease ... See more keywords
M22 GENOME-WIDE METHYLOME AND TRANSCRIPTOME PROFILES OF MANIC EPISODE IN BIPOLAR DISORDER
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DOI: 10.1016/j.euroneuro.2017.08.329
Abstract: Background Bipolar Disorder (BD) is a highly heritable psychiatric disorder. More than two thirds of BD patients have recurrent episodes throughout lifetime. To explore the underlying biological mechanisms of manic episode in BD, the current… read more here.
Keywords: genome wide; methylome transcriptome; bipolar disorder; episode ... See more keywords
DNA methylome and transcriptome landscapes revealed differential characteristics of dioecious flowers in papaya
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DOI: 10.1038/s41438-020-0298-0
Abstract: Separate sexes in dioecious plants display different morphology and physiological characteristics. The differences between the two sexes lie in their highly differentiated floral characteristics and in sex-related phenotype, which is genetically determined and epigenetically modified.… read more here.
Keywords: methylation; methylome transcriptome; dna methylome; transcriptome landscapes ... See more keywords
Methylome and Transcriptome-Based Integration Analysis Identified Molecular Signatures Associated With Meningitis Induced by Glaesserella parasuis
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.840399
Abstract: Glaesserella parasuis (G. parasuis) can elicit serious inflammatory responses and cause meningitis in piglets. Previous epigenetic studies have indicated that alterations in host DNA methylation may modify the inflammatory response to bacterial infection. However, to… read more here.
Keywords: methylation; meningitis; dna methylation; parasuis ... See more keywords