S N H -ARYLAMINATION OF 1-METHYLQUINOLIN-2(1 H )-ONE NITRO DERIVATIVES
Sign Up to like & getrecommendations! Published in 2021 at "Chemistry of Heterocyclic Compounds"
DOI: 10.1007/5947
Abstract: Arylamino derivatives of both the corresponding nitroquinolones and nitrosoquinolones were first obtained by direct nucleophilic substitution of hydrogen in the molecules of 1-methyl-5(6,7,8)-nitroquinolin-2(1 Н )-ones. read more here.
Keywords: methylquinolin one; arylamination methylquinolin; one nitro; nitro derivatives ... See more keywords
Discovery of 1-hydroxy-2-methylquinolin-4(1H)-one derivatives as new cytochrome bd oxidase inhibitors for tuberculosis therapy.
Sign Up to like & getrecommendations! Published in 2022 at "European journal of medicinal chemistry"
DOI: 10.2139/ssrn.4215666
Abstract: The cytochrome bcc-aa3 oxidase (Cyt-bcc) of Mycobacterium tuberculosis (Mtb) is a promising anti-tuberculosis target. However, when Cyt-bcc is inhibited, cytochrome bd terminal oxidase (Cyt-bd) can still maintain the activity of the respiratory chain and drive… read more here.
Keywords: hydroxy methylquinolin; bcc; methylquinolin one; oxidase ... See more keywords