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Published in 2019 at "Neurochemical Research"
DOI: 10.1007/s11064-019-02929-8
Abstract: This work evaluated the in vitro effect of thiazolidin-4-ones on the activity of AChE (total and isoforms) isolated from the cerebral cortex, hippocampus, and lymphocytes. Kinetic parameters were evaluated and molecular docking was performed. Our…
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Keywords:
vitro effects;
effects methylthio;
methylsulfonyl phenyl;
activity ... See more keywords
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Published in 2018 at "European journal of medicinal chemistry"
DOI: 10.1016/j.ejmech.2018.04.007
Abstract: A novel series of methylsulfonyl phenyl derivatives has been designed and synthesized to evaluate their COX-2 inhibitory activity along with anti-convulsant potential. In-vitro evaluation revealed that two compounds MTL-1 and MTL-2 appeared as most potent…
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Keywords:
ptz;
mtl;
phenyl derivatives;
cox ... See more keywords