Histone arginine methyltransferase CARM1 selective inhibitor TP-064 induces apoptosis in endometrial cancer.
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DOI: 10.1016/j.bbrc.2022.02.086
Abstract: Histone modification is the key epigenetic mechanism that regulates gene expression. Coactivator-associated arginine methyltransferase 1 (CARM1) is an arginine methyltransferase that catalyzes dimethylation of histone H3 (H3R17) at arginine 17. Lately, it has been suggested… read more here.
Keywords: cancer; arginine methyltransferase; methyltransferase carm1; endometrial cancer ... See more keywords