Catechol-O-methyltransferase Inhibitors from Calendula officinalis Leaf
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DOI: 10.3390/molecules28031333
Abstract: Calendula officinalis is commonly known as marigold and its flowers are used in herbal medicines, cosmetics, perfumes, dyes, pharmaceutical preparations, and food products. However, the utility of its leaves has not been studied in depth.… read more here.
Keywords: catechol methyltransferase; officinalis leaf; calendula officinalis; methyltransferase inhibitors ... See more keywords
Expanding the Structural Diversity of DNA Methyltransferase Inhibitors
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DOI: 10.3390/ph14010017
Abstract: Inhibitors of DNA methyltransferases (DNMTs) are attractive compounds for epigenetic drug discovery. They are also chemical tools to understand the biochemistry of epigenetic processes. Herein, we report five distinct inhibitors of DNMT1 characterized in enzymatic… read more here.
Keywords: biochemistry; structural diversity; diversity dna; methyltransferase inhibitors ... See more keywords