Methyltransferase like 13 mediates the translation of Snail in head and neck squamous cell carcinoma
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DOI: 10.1038/s41368-021-00130-8
Abstract: Methyltransferase like 13 (METTL13), a kind of methyltransferase, is implicated in protein binding and synthesis. The upregulation of METTL13 has been reported in a variety of tumors. However, little was known about its potential function… read more here.
Keywords: neck squamous; mettl13; methyltransferase like; methyltransferase ... See more keywords
Mechanism of methyltransferase like 3 in epithelial-mesenchymal transition process, invasion, and metastasis in esophageal cancer.
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DOI: 10.1080/21655979.2021.1994721
Abstract: Methyltransferase like 3 (METTL3) has been identified to serve as a definitive inducer in cancer progression. This study sought to analyze the regulatory mechanism of METTL3 in epithelial-mesenchymal transition (EMT), invasion, and metastasis in esophageal… read more here.
Keywords: mir 20a; invasion; methyltransferase like; mettl3 ... See more keywords
The potential role of methyltransferase-like 5 in deficient mismatch repair of uterine corpus endometrial carcinoma
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DOI: 10.1080/21655979.2022.2036912
Abstract: ABSTRACT To explore the potential function of methyltransferase-like 5 (METTL5) in uterine corpus endometrial carcinoma (UCEC) and verify the relationship between deficient DNA mismatch repair (MMR) and METTL5. We used bioinformatics to predict the possible… read more here.
Keywords: endometrial carcinoma; mettl5; methyltransferase like; uterine corpus ... See more keywords
Methyltransferase-like 3 induces the development of cervical cancer by enhancing insulin-like growth factor 2 mRNA-binding proteins 3-mediated apoptotic chromatin condensation inducer 1 mRNA stability
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DOI: 10.1080/21655979.2022.2044261
Abstract: ABSTRACT N6-methyladenosine (m6A) plays a critical role in the tumorigenesis of cervical cancer (CC). Here, we aimed to investigate the potential role of methyltransferase-like 3 (METTL3) in CC. Gene expression was determined via real-time quantitative… read more here.
Keywords: cervical cancer; mrna stability; growth; methyltransferase like ... See more keywords
Methyltransferase-like 3 silenced inhibited the ferroptosis development via regulating the glutathione peroxidase 4 levels in the intracerebral hemorrhage progression
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DOI: 10.1080/21655979.2022.2084494
Abstract: ABSTRACT This study examined the effects of methyltransferase-like 3 (METTL3) on ferroptosis during intracerebral hemorrhage (ICH) progression. The brain microvascular endothelial cells (BMVECs) were stimulated with oxygen and glucose deprivation (OGD) and hemin to establish… read more here.
Keywords: methyltransferase like; glutathione peroxidase; ferroptosis; intracerebral hemorrhage ... See more keywords
METTL14 promotes migration and invasion of choroidal melanoma by targeting RUNX2 mRNA via m6A modification
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DOI: 10.1111/jcmm.17577
Abstract: The modification of N6‐methyladenosine is involved in the progression of various cancers. This study aimed to clarify its regulatory mechanism in the pathogenesis of choroidal melanoma. Expression of methyltransferase‐like 14 in choroidal melanoma or normal… read more here.
Keywords: choroidal melanoma; methyltransferase like; invasion; melanoma ... See more keywords
Methyltransferase like 3 enhances pinin mRNA stability through N6‐methyladenosine modification to augment tumourigenesis of colon adenocarcinoma
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DOI: 10.1113/ep090273
Abstract: What is the central question of this study? What is the role of pinin (PNN) in the malignant phenotype of colon adenocarcinoma cells and the underlying mechanism? What is the main finding and its importance?… read more here.
Keywords: like enhances; colon adenocarcinoma; methyltransferase like; colon ... See more keywords
Methyltransferase-like 3 Aggravates HCC Development via Mediating N6-Methyladenosine of Ubiquitin-Specific Protease 7
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DOI: 10.1155/2022/6167832
Abstract: We aimed to investigate the role of methyltransferase-like 3 (METTL3) in regulating HCC by mediating m6A level of ubiquitin-specific protease (USP7). METTL3 levels and m6A contents in HCC tissues and cells were detected. Potential correlations… read more here.
Keywords: specific protease; hcc; methyltransferase like; ubiquitin specific ... See more keywords
METTL16, Methyltransferase-Like Protein 16: Current Insights into Structure and Function
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DOI: 10.3390/ijms22042176
Abstract: Methyltransferase-like protein 16 (METTL16) is a human RNA methyltransferase that installs m6A marks on U6 small nuclear RNA (U6 snRNA) and S-adenosylmethionine (SAM) synthetase pre-mRNA. METTL16 also controls a significant portion of m6A epitranscriptome by… read more here.
Keywords: methyltransferase like; rna; methyltransferase; like protein ... See more keywords