Methyltransferase like 13 mediates the translation of Snail in head and neck squamous cell carcinoma
Sign Up to like & getrecommendations! Published in 2021 at "International Journal of Oral Science"
DOI: 10.1038/s41368-021-00130-8
Abstract: Methyltransferase like 13 (METTL13), a kind of methyltransferase, is implicated in protein binding and synthesis. The upregulation of METTL13 has been reported in a variety of tumors. However, little was known about its potential function… read more here.
Keywords: neck squamous; mettl13; methyltransferase like; methyltransferase ... See more keywords
Mechanism of methyltransferase like 3 in epithelial-mesenchymal transition process, invasion, and metastasis in esophageal cancer.
Sign Up to like & getrecommendations! Published in 2021 at "Bioengineered"
DOI: 10.1080/21655979.2021.1994721
Abstract: Methyltransferase like 3 (METTL3) has been identified to serve as a definitive inducer in cancer progression. This study sought to analyze the regulatory mechanism of METTL3 in epithelial-mesenchymal transition (EMT), invasion, and metastasis in esophageal… read more here.
Keywords: mir 20a; invasion; methyltransferase like; mettl3 ... See more keywords
The potential role of methyltransferase-like 5 in deficient mismatch repair of uterine corpus endometrial carcinoma
Sign Up to like & getrecommendations! Published in 2022 at "Bioengineered"
DOI: 10.1080/21655979.2022.2036912
Abstract: ABSTRACT To explore the potential function of methyltransferase-like 5 (METTL5) in uterine corpus endometrial carcinoma (UCEC) and verify the relationship between deficient DNA mismatch repair (MMR) and METTL5. We used bioinformatics to predict the possible… read more here.
Keywords: endometrial carcinoma; mettl5; methyltransferase like; uterine corpus ... See more keywords
Methyltransferase-like 3 induces the development of cervical cancer by enhancing insulin-like growth factor 2 mRNA-binding proteins 3-mediated apoptotic chromatin condensation inducer 1 mRNA stability
Sign Up to like & getrecommendations! Published in 2022 at "Bioengineered"
DOI: 10.1080/21655979.2022.2044261
Abstract: ABSTRACT N6-methyladenosine (m6A) plays a critical role in the tumorigenesis of cervical cancer (CC). Here, we aimed to investigate the potential role of methyltransferase-like 3 (METTL3) in CC. Gene expression was determined via real-time quantitative… read more here.
Keywords: cervical cancer; mrna stability; growth; methyltransferase like ... See more keywords
Methyltransferase-like 3 silenced inhibited the ferroptosis development via regulating the glutathione peroxidase 4 levels in the intracerebral hemorrhage progression
Sign Up to like & getrecommendations! Published in 2022 at "Bioengineered"
DOI: 10.1080/21655979.2022.2084494
Abstract: ABSTRACT This study examined the effects of methyltransferase-like 3 (METTL3) on ferroptosis during intracerebral hemorrhage (ICH) progression. The brain microvascular endothelial cells (BMVECs) were stimulated with oxygen and glucose deprivation (OGD) and hemin to establish… read more here.
Keywords: methyltransferase like; glutathione peroxidase; ferroptosis; intracerebral hemorrhage ... See more keywords
Decreased METTL3 in atrial myocytes promotes atrial fibrillation
Sign Up to like & getrecommendations! Published in 2025 at "Europace"
DOI: 10.1093/europace/euaf021
Abstract: Abstract Aims Methyltransferase like 3 (METTL3) plays a crucial role in cardiovascular diseases, but its involvement in atrial fibrillation (AF) remains unclear. The study aims to explore the relationship between METTL3 and AF in atrial… read more here.
Keywords: methyltransferase like; atrial myocytes; decreased mettl3; mettl3 atrial ... See more keywords
METTL14 promotes migration and invasion of choroidal melanoma by targeting RUNX2 mRNA via m6A modification
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Cellular and Molecular Medicine"
DOI: 10.1111/jcmm.17577
Abstract: The modification of N6‐methyladenosine is involved in the progression of various cancers. This study aimed to clarify its regulatory mechanism in the pathogenesis of choroidal melanoma. Expression of methyltransferase‐like 14 in choroidal melanoma or normal… read more here.
Keywords: choroidal melanoma; methyltransferase like; invasion; melanoma ... See more keywords
Methyltransferase like 3 enhances pinin mRNA stability through N6‐methyladenosine modification to augment tumourigenesis of colon adenocarcinoma
Sign Up to like & getrecommendations! Published in 2022 at "Experimental Physiology"
DOI: 10.1113/ep090273
Abstract: What is the central question of this study? What is the role of pinin (PNN) in the malignant phenotype of colon adenocarcinoma cells and the underlying mechanism? What is the main finding and its importance?… read more here.
Keywords: like enhances; colon adenocarcinoma; methyltransferase like; colon ... See more keywords
Methyltransferase-like 3 Aggravates HCC Development via Mediating N6-Methyladenosine of Ubiquitin-Specific Protease 7
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Oncology"
DOI: 10.1155/2022/6167832
Abstract: We aimed to investigate the role of methyltransferase-like 3 (METTL3) in regulating HCC by mediating m6A level of ubiquitin-specific protease (USP7). METTL3 levels and m6A contents in HCC tissues and cells were detected. Potential correlations… read more here.
Keywords: specific protease; hcc; methyltransferase like; ubiquitin specific ... See more keywords
The expression landscape and clinical significance of methyltransferase-like 17 in human cancer and hepatocellular carcinoma: a pan-cancer analysis using multiple databases
Sign Up to like & getrecommendations! Published in 2025 at "Cancer Cell International"
DOI: 10.1186/s12935-024-03616-7
Abstract: Methyltransferase-like (METTL) family protein plays a crucial role in the progression of malignancies. However, the function of METTL17 across pan-cancers, especially in hepatocellular carcinoma (HCC) is still poorly understood. All original data were downloaded from… read more here.
Keywords: cancer; methyltransferase like; analysis; hepatocellular carcinoma ... See more keywords
Methyltransferase-like 3 represents a prospective target for the diagnosis and treatment of kidney diseases
Sign Up to like & getrecommendations! Published in 2024 at "Human Genomics"
DOI: 10.1186/s40246-024-00692-8
Abstract: Kidney disease is marked by complex pathological mechanisms and significant therapeutic hurdles, resulting in high morbidity and mortality rates globally. A deeper understanding of the fundamental processes involved can aid in identifying novel therapeutic targets… read more here.
Keywords: diagnosis; treatment; methyltransferase like; kidney diseases ... See more keywords