Methylation of the Hippo effector YAP by the methyltransferase SETD7 drives myocardial ischemic injury: a translational study.
Sign Up to like & getrecommendations! Published in 2022 at "Cardiovascular research"
DOI: 10.1093/cvr/cvac102
Abstract: AIMS Methylation of non-histone proteins is emerging as a central regulatory mechanism in health and disease. The methyltransferase SETD7 has shown to methylate and alter the function of a variety of proteins in vitro, however… read more here.
Keywords: methylation; myocardial ischemic; ischemic injury; setd7 ... See more keywords
P5378The methyltransferase SETD7 promotes myocardial ischemic injury by activating Hippo signalling
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DOI: 10.1093/eurheartj/ehz746.0339
Abstract: Despite significant advances in coronary revascularization, acute myocardial infarction remains the leading cause of heart failure and death worldwide. The Hippo pathway is a master regulator of cell survival during myocardial ischemia. Upon cellular stress,… read more here.
Keywords: hippo; microscopy; methyltransferase setd7; setd7 ... See more keywords
A Systematic Review to Define the Multi-Faceted Role of Lysine Methyltransferase SETD7 in Cancer
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DOI: 10.3390/cancers14061414
Abstract: Simple Summary The protein methyltransferase SETD7 is essential for epigenetic regulation through methylation of histone H3 and non-histone proteins, including cell cycle, apoptosis and metastasis regulators. This multi-faceted role of SETD7 is cell context-and tissue… read more here.
Keywords: systematic review; setd7; cancer; methyltransferase setd7 ... See more keywords