Articles with "methyltransferase treatment" as a keyword



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Novel Inhibitors of Nicotinamide-N-Methyltransferase for the Treatment of Metabolic Disorders

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Published in 2021 at "Molecules"

DOI: 10.3390/molecules26040991

Abstract: Nicotinamide-N-methyltransferase (NNMT) is a cytosolic enzyme catalyzing the transfer of a methyl group from S-adenosyl-methionine (SAM) to nicotinamide (Nam). It is expressed in many tissues including the liver, adipose tissue, and skeletal muscle. Its expression… read more here.

Keywords: treatment metabolic; methyltransferase treatment; methyltransferase; novel inhibitors ... See more keywords