Photoradiosynthesis of 68Ga-Labeled HBED-CC-Azepin-MetMAb for Immuno-PET of c-MET Receptors.
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DOI: 10.1021/acs.bioconjchem.9b00342
Abstract: In an alternative approach for radiotracer design, a photoactivatable HBED-CC-PEG3-ArN3 chelate was synthesized and photoconjugated to the anti-c-MET antibody MetMAb (onartuzumab). Photoconjugation gave the functionalized protein HBED-CC-azepin-MetMAb with a photochemical conversion of 18.5 ± 0.5%… read more here.
Keywords: photoradiosynthesis 68ga; metmab; immuno pet; hbed azepin ... See more keywords