Design and Evaluation of Bilayer Matrix Tablet of Metoprolol Tartrate and Lisinopril Maleate
Sign Up to like & getrecommendations! Published in 2017 at "Advances in Polymer Technology"
DOI: 10.1002/adv.21582
Abstract: The objective of study was to design bilayer matrix tablet of metoprolol tartrate and lisinopril maleate. The direct compression method was used for preparation of both layers. Precompression and postcompression parameters were evaluated. USP Type… read more here.
Keywords: metoprolol tartrate; lisinopril maleate; release;
Robustness of barrier membrane coated metoprolol tartrate matrix tablets: Drug release evaluation under physiologically relevant in vitro conditions
Sign Up to like & getrecommendations! Published in 2018 at "International Journal of Pharmaceutics"
DOI: 10.1016/j.ijpharm.2018.04.005
Abstract: &NA; Robust in vitro drug release behavior is an important feature of extended release (ER) hydrophilic matrix formulations for accurate prediction of in vivo drug release. In this study, ER hydrophilic matrix tablets of metoprolol… read more here.
Keywords: barrier membrane; drug release; metoprolol tartrate; matrix tablets ... See more keywords
In vitro and in vivo assessment of Adansonia digitata mucilage as a matrix former in modified release tablets of metoprolol tartrate
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Drug Delivery Science and Technology"
DOI: 10.1016/j.jddst.2019.101227
Abstract: Abstract The study was aimed to investigate the ability of Adansonia digitata mucilage (ADM) a new hydrophilic plant polymeric material, in modifying metoprolol tartrate (MPT) release from matrix tablet formulations in comparison with a semi… read more here.
Keywords: modified release; metoprolol tartrate; drug; digitata mucilage ... See more keywords
Advancing USP compendial methods for fixed dose combinations: A case study of metoprolol tartrate and hydrochlorothiazide tablets
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Pharmaceutical Analysis"
DOI: 10.1016/j.jpha.2018.12.003
Abstract: The current United States Pharmacopeia–National Formulary (USP–NF) includes more than 250 monographs of fixed dose combinations (FDCs), and some of them need to be updated due to incompleteness of impurity profiles and obsolescence of analytical… read more here.
Keywords: metoprolol tartrate; tartrate hydrochlorothiazide; case study;
Role of hesperidin and fresh orange juice in altering the bioavailability of beta-blocker, metoprolol tartrate. An in vivo model
Sign Up to like & getrecommendations! Published in 2022 at "Xenobiotica"
DOI: 10.1080/00498254.2022.2067507
Abstract: Abstract The aim of my study was to find the effect of co-administrating orange juice and hesperidin on the bioavailability of metoprolol tartrate in rabbits. Metoprolol tartrate (10 mg/kg) was given orally to rabbits with hesperidin… read more here.
Keywords: metoprolol tartrate; tartrate; orange juice; bioavailability ... See more keywords
Preparation and evaluation of metoprolol tartrate sustained-release pellets using hot melt extrusion combined with hot melt coating
Sign Up to like & getrecommendations! Published in 2017 at "Drug Development and Industrial Pharmacy"
DOI: 10.1080/03639045.2017.1287715
Abstract: Abstract The objective of this study was to prepare and evaluate metoprolol tartrate sustained-release pellets. Cores were prepared by hot melt extrusion and coated pellets were prepared by hot melt coating. Cores were found to… read more here.
Keywords: drug; sustained release; hot melt; metoprolol tartrate ... See more keywords
FORMULATION AND EVALUATION OF TRANSDERMAL PATCHES OF METOPROLOL TARTRATE USING PERMEATION ENHANCERS OF NATURAL AND SYNTHETIC ORIGIN
Sign Up to like & getrecommendations! Published in 2019 at "International Journal of Applied Pharmaceutics"
DOI: 10.22159/ijap.2019v11i5.32759
Abstract: Objective: Oral metoprolol tartrate has a short elimination half-life (2-3h) and low bioavailability undergoes extensive first-pass metabolism and frequent dosing. The aim of the present investigation was to formulate, develop and evaluate metoprolol tartrate transdermal… read more here.
Keywords: metoprolol tartrate; permeation; transdermal patches; formulation evaluation ... See more keywords