Articles with "metrnl" as a keyword



Correlation of serum meteorin-like concentrations with diabetic nephropathy.

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Published in 2020 at "Diabetes research and clinical practice"

DOI: 10.1016/j.diabres.2020.108443

Abstract: OBJECTIVE Meteorin-like (Metrnl), a secreted myokine, is induced in white adipose tissue during cold exposure and in muscle after exercise. The present investigation aim to determine the hypothesis that serum Metrnl concentrations are correlated with… read more here.

Keywords: metrnl; metrnl concentrations; diabetic nephropathy; meteorin like ... See more keywords
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Meteorin-like protein attenuates doxorubicin-induced cardiotoxicity via activating cAMP/PKA/SIRT1 pathway

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Published in 2020 at "Redox Biology"

DOI: 10.1016/j.redox.2020.101747

Abstract: Meteorin-like (METRNL) protein is a newly identified myokine that functions to modulate energy expenditure and inflammation in adipose tissue. Herein, we aim to investigate the potential role and molecular basis of METRNL in doxorubicin (DOX)-induced… read more here.

Keywords: metrnl; camp pka; induced cardiotoxicity; dox ... See more keywords
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Metrnl deficiency decreases blood HDL cholesterol and increases blood triglyceride

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Published in 2020 at "Acta Pharmacologica Sinica"

DOI: 10.1038/s41401-020-0368-8

Abstract: Dyslipidemia is a risk factor for cardiovascular diseases and type 2 diabetes. Several adipokines play important roles in modulation of blood lipids. Metrnl is a recently identified adipokine, and adipose Metrnl participates in regulation of… read more here.

Keywords: metrnl; cholesterol; blood; blood triglyceride ... See more keywords

Serum Metrnl is associated with the presence and severity of coronary artery disease

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Published in 2019 at "Journal of Cellular and Molecular Medicine"

DOI: 10.1111/jcmm.13915

Abstract: Meteorinā€like (Metrnl) is a novel adipokine that is highly expressed in white adipose tissue. Metrnl stimulates energy expenditure and improves glucose tolerance in rodents. However, whether Metrnl plays a role in coronary artery disease (CAD)… read more here.

Keywords: metrnl; coronary artery; severity; serum metrnl ... See more keywords

Exploration of meteorin-like peptide (metrnl) predictors in type 2 diabetic patients: the potential role of irisin, and other biochemical parameters

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Published in 2022 at "Hormone Molecular Biology and Clinical Investigation"

DOI: 10.1515/hmbci-2022-0037

Abstract: Abstract Objectives Meteorin-like peptide (Metrnl), the newly discovered adipokines involves in glucose and lipid metabolism and energy homeostasis. The aim of the present study was to explore the potential predictors of Metrnl by emphasizing the… read more here.

Keywords: irisin; type diabetic; meteorin like; metrnl ... See more keywords

Circulating Meteorin-like Levels in Patients with type 2 Diabetes Mellitus: A Meta-analysis.

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Published in 2020 at "Current pharmaceutical design"

DOI: 10.2174/1381612826666201007163930

Abstract: BACKGROUND Meteorin-like (Metrnl) is a newly identified adipokine implicated in the pathogenesis of type 2 diabetes mellitus (T2DM), yet data on the circulating levels of Metrnl in patients with T2DM are controversial. To derive a… read more here.

Keywords: metrnl; analysis; circulating metrnl; meteorin like ... See more keywords
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Metrnl Alleviates Lipid Accumulation by Modulating Mitochondrial Homeostasis in Diabetic Nephropathy

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Published in 2023 at "Diabetes"

DOI: 10.2337/db22-0680

Abstract: Ectopic lipid accumulation in renal tubules is closely related to the pathogenesis of diabetic kidney disease (DKD), and mitochondrial dysfunction is thought to play a key role in lipid accumulation. Therefore, maintaining mitochondrial homeostasis holds… read more here.

Keywords: kidney; accumulation; metrnl; mitochondrial homeostasis ... See more keywords
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Serum Metrnl levels are decreased in subjects with overweight or obesity and are independently associated with adverse lipid profile

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Published in 2022 at "Frontiers in Endocrinology"

DOI: 10.3389/fendo.2022.938341

Abstract: Background Meteorin-like (Metrnl), a novel adipokine, is highly expressed in adipose tissue and has a beneficial effect on energy metabolism. However, data on circulating Metrnl levels in obesity are scarce and inconsistent. This study aimed… read more here.

Keywords: overweight obesity; metrnl levels; metrnl; obesity independently ... See more keywords