Sustained Simultaneous Delivery of Metronidazole and Doxycycline From Polycaprolactone Matrices Designed for Intravaginal Treatment of Pelvic Inflammatory Disease.
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DOI: 10.1016/j.xphs.2017.09.033
Abstract: Poly(ɛ-caprolactone) (PCL) intravaginal matrices were produced for local delivery of a combination of antibacterials, by rapidly cooling a mixture of drug powders dispersed in PCL solution. Matrices loaded with different combinations of metronidazole (10%, 15%,… read more here.
Keywords: inflammatory disease; delivery; pelvic inflammatory; metronidazole ... See more keywords