Effect of metronidazole resistance on Helicobacter pylori eradication regimens
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Digestive Diseases"
DOI: 10.1111/1751-2980.13142
Abstract: Guidelines suggest bismuth‐containing quadruple therapy (BQT) or concomitant therapy (CT) as first‐line therapy in our geographic area. Both schedules contain metronidazole. We aimed to evaluate the effect of metronidazole resistance to Helicobacter pylori (H. pylori)… read more here.
Keywords: metronidazole resistance; effect metronidazole; pylori eradication; resistance helicobacter ... See more keywords
The Role of Iron Status in the Early Progression of Metronidazole Resistance in Trichomonas vaginalis Under Microaerophilic Conditions
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Eukaryotic Microbiology"
DOI: 10.1111/jeu.12671
Abstract: Trichomonas vaginalis is the etiological agent of human trichomoniasis. Metronidazole has high treatment success rate among trichomoniasis patients. However, metronidazole‐resistant T. vaginalis has been reported, contributing in an increasing number of refractory cases. The mechanism… read more here.
Keywords: trichomonas vaginalis; microaerophilic conditions; resistant strains; metronidazole resistance ... See more keywords
Five alternative Helicobacter pylori antibiotics to counter high levofloxacin and metronidazole resistance in the Dominican Republic
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DOI: 10.1371/journal.pone.0213868
Abstract: The prevalence of Helicobacter pylori resistance to levofloxacin and metronidazole was high in the Dominican Republic. We used two-fold agar dilution method to determine the minimum inhibitory concentration of five alternative antibiotics in 63 Dominican… read more here.
Keywords: dominican republic; levofloxacin metronidazole; metronidazole resistance; resistance ... See more keywords
The effects of identical nim gene-insertion sequence combinations on the expression of the nim genes and metronidazole resistance in Bacteroides fragilis strains.
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DOI: 10.2139/ssrn.4375659
Abstract: In this study we examined whether the same nim gene-insertion sequence (IS) element combinations give rise to the same expression levels as they harbor shared IS element-borne promoters. From our quantitative analysis, we found that… read more here.
Keywords: metronidazole resistance; nim gene; insertion sequence; gene insertion ... See more keywords
Proteomic analysis of metronidazole resistance in the human facultative pathogen Bacteroides fragilis
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2023.1158086
Abstract: The anaerobic gut bacteria and opportunistic pathogen Bacteroides fragilis can cause life-threatening infections when leaving its niche and reaching body sites outside of the gut. The antimicrobial metronidazole is a mainstay in the treatment of… read more here.
Keywords: metronidazole resistance; bacteroides fragilis; resistance; pathogen bacteroides ... See more keywords