Eliminating METTL1‐mediated accumulation of PMN‐MDSCs prevents hepatocellular carcinoma recurrence after radiofrequency ablation
Sign Up to like & getrecommendations! Published in 2022 at "Hepatology"
DOI: 10.1002/hep.32585
Abstract: Background and Aims: Radiofrequency ablation (RFA) is an important curative therapy in hepatocellular carcinoma (HCC), but recurrence rate remains as high as all the other HCC therapeutic modalities. Methyltransferase 1 (METTL1), an enzyme for m7G… read more here.
Keywords: rfa; accumulation; pmn mdscs; recurrence ... See more keywords
METTL1 overexpression is correlated with poor prognosis and promotes hepatocellular carcinoma via PTEN
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DOI: 10.1007/s00109-019-01830-9
Abstract: RNA methylation is emerging as an important regulator of gene expression. Dysregulation of methyltransferase that is essential for RNA modification contributes to the development and progression of human cancers. Here we show that methyltransferase-like 1… read more here.
Keywords: hepatocellular carcinoma; hcc; via pten; expression ... See more keywords
Prognostic role of METTL1 in glioma
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DOI: 10.1186/s12935-021-02346-4
Abstract: Background Current treatment options for glioma are limited, and the prognosis of patients with glioma is poor as the available drugs show low therapeutic efficacy. Furthermore, the molecular mechanisms associated with glioma remain poorly understood.… read more here.
Keywords: mettl1 glioma; glioma; mettl1 expression; patients glioma ... See more keywords