METTL3 and ALKBH5 oppositely regulate m6A modification of TFEB mRNA, which dictates the fate of hypoxia/reoxygenation-treated cardiomyocytes
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DOI: 10.1080/15548627.2019.1586246
Abstract: ABSTRACT N6-methyladenosine (m6A) mRNA modifications play critical roles in various biological processes. However, no study addresses the role of m6A in macroautophagy/autophagy. Here, we show that m6A modifications are increased in H/R-treated cardiomyocytes and ischemia/reperfusion… read more here.
Keywords: protein; treated cardiomyocytes; mettl3 alkbh5; autophagy ... See more keywords