Discovery of substituted indole derivatives as allosteric inhibitors of m6A‐RNA methyltransferase, METTL3‐14 complex
Sign Up to like & getrecommendations! Published in 2022 at "Drug Development Research"
DOI: 10.1002/ddr.21910
Abstract: m6A RNA methyltransferase (METTL3‐14) catalyzes the methylation of adenosine in mRNA and plays important roles in mRNA functions, and it has been implicated in the progression of multiple cancers, including acute myeloid leukemia (AML). In… read more here.
Keywords: m6a rna; mettl3 complex; rna methyltransferase; methyltransferase mettl3 ... See more keywords