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   Articles with "mettl5" as a keyword



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The potential role of methyltransferase-like 5 in deficient mismatch repair of uterine corpus endometrial carcinoma

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recommendations! Published in 2022 at "Bioengineered"

DOI: 10.1080/21655979.2022.2036912

Abstract: ABSTRACT To explore the potential function of methyltransferase-like 5 (METTL5) in uterine corpus endometrial carcinoma (UCEC) and verify the relationship between deficient DNA mismatch repair (MMR) and METTL5. We used bioinformatics to predict the possible… read more here.

Keywords: endometrial carcinoma; mettl5; methyltransferase like; uterine corpus ... See more keywords
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Expression and prognostic potential of ribosome 18S RNA m6A methyltransferase METTL5 in gastric cancer

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recommendations! Published in 2021 at "Cancer Cell International"

DOI: 10.1186/s12935-021-02274-3

Abstract: Background Ribosomal RNA N6-methyltransferase METTL5 was reported to catalyze m 6 A in 18S rRNA. We aimed to investigate the expression and prognostic features of METTL5 in gastric cancer (GC). Methods In this study, 168… read more here.

Keywords: mettl5; gastric cancer; mettl5 protein; expression ... See more keywords
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The 18S ribosomal RNA m6A methyltransferase Mettl5 is required for normal walking behavior in Drosophila

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recommendations! Published in 2020 at "EMBO reports"

DOI: 10.15252/embr.201949443

Abstract: RNA modifications have recently emerged as an important layer of gene regulation. N6‐methyladenosine (m6A) is the most prominent modification on eukaryotic messenger RNA and has also been found on noncoding RNA, including ribosomal and small… read more here.

Keywords: ribosomal rna; mettl5; 18s ribosomal; methyltransferase ... See more keywords
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Inhibition of METTL5 improves preimplantation development of mouse somatic cell nuclear transfer embryos.

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recommendations! Published in 2022 at "Reproduction"

DOI: 10.1530/rep-22-0169

Abstract: N6-methyladenosine (m6A) is one of the most important epigenetic modifications in eukaryotic RNAs that regulates development and diseases. It is identified by several proteins. Methyltransferase-like 5 (METTL5), an enzyme that methylates 18S rRNA m6A, controls… read more here.

Keywords: mettl5; development; nuclear transfer; somatic cell ... See more keywords