Transcriptomics Reveals the Mevalonate and Cholesterol Pathways Blocking as Part of the Bacterial Cyclodipeptides Cytotoxic Effects in HeLa Cells of Human Cervix Adenocarcinoma
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2022.790537
Abstract: The incidence of human cervix adenocarcinoma (CC) caused by papillomavirus genome integration into the host chromosome is the third most common cancer among women. Bacterial cyclodipeptides (CDPs) exert cytotoxic effects in human cervical cancer HeLa… read more here.
Keywords: hela cells; mevalonate cholesterol; expression; human cervix ... See more keywords
HSF1 Regulates Mevalonate and Cholesterol Biosynthesis Pathways
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DOI: 10.3390/cancers11091363
Abstract: Heat shock factor 1 (HSF1) is an essential transcription factor in cellular adaptation to various stresses such as heat, proteotoxic stress, metabolic stress, reactive oxygen species, and heavy metals. HSF1 promotes cancer development and progression,… read more here.
Keywords: hsf1; cholesterol; cholesterol biosynthesis; biosynthesis pathways ... See more keywords