Articles with "mevidalen" as a keyword



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Safety, Tolerability, and Pharmacokinetics of Mevidalen (LY3154207), a Centrally Acting Dopamine D1 Receptor-Positive Allosteric Modulator, in Patients With Parkinson Disease.

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Published in 2021 at "Clinical pharmacology in drug development"

DOI: 10.1002/cpdd.1039

Abstract: Mevidalen (LY3154207) is a positive allosteric modulator of the dopamine D1 receptor that enhances the affinity of dopamine for the D1 receptor. The safety, tolerability, motor effects, and pharmacokinetics of mevidalen were studied in patients… read more here.

Keywords: dopamine receptor; patients parkinson; mevidalen; parkinson disease ... See more keywords