MEX3A impairs DNA mismatch repair signaling and mediates acquired temozolomide resistance in glioblastoma.
Sign Up to like & getrecommendations! Published in 2022 at "Cancer research"
DOI: 10.1158/0008-5472.can-22-2036
Abstract: MutS protein homolog 2 (MSH2) is a key element involved in the DNA mismatch repair system, which is responsible for recognizing and repairing mispaired bases. Simultaneously, MSH2 identifies DNA adducts induced by temozolomide (TMZ) and… read more here.
Keywords: mismatch repair; dna mismatch; msh2; mex3a ... See more keywords
Grass Carp Mex3A Promotes Ubiquitination and Degradation of RIG-I to Inhibit Innate Immune Response
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.909315
Abstract: As one of the Mex3 family members, Mex3A is crucial in cell proliferation, migration, and apoptosis in mammals. In this study, a novel gene homologous to mammalian Mex3A (named CiMex3A, MW368974) was cloned and identified… read more here.
Keywords: mex3a; carp mex3a; grass carp; rig ... See more keywords