Porphyromonas gingivalis Mfa1 fimbria putatively binds to TLR2 and induces both IL-6 and IL-8 production in human bronchial epithelial cells.
Sign Up to like & getrecommendations! Published in 2021 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2021.12.003
Abstract: Porphyromonas gingivalis (Pg) a major periodontal pathogen involved in periodontal disease development and progression. Moreover, Pg has two fimbriae surface proteins (FimA and Mfa1) that are genetically distinct and make-up the fimbrial shaft which in-turn… read more here.
Keywords: functional response; porphyromonas gingivalis; human bronchial; bronchial epithelial ... See more keywords
Structural and antigenic characterization of a novel genotype of Mfa1 fimbriae in Porphyromonas gingivalis
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Oral Microbiology"
DOI: 10.1080/20002297.2023.2215551
Abstract: ABSTRACT Background Mfa1 fimbriae of the periodontal pathogen Porphyromonas gingivalis are responsible for biofilm formation and comprise five proteins: Mfa1–5. Two major genotypes, mfa170 and mfa153, encode major fimbrillin. The mfa170 genotype is further divided… read more here.
Keywords: mfa1; genotype; mfa1 fimbriae; porphyromonas gingivalis ... See more keywords
Porphyromonas gingivalis Fimbriae Induce Osteoclastogenesis via Toll-like Receptors in RAW264 Cells
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DOI: 10.3390/ijms232315293
Abstract: The effect of Mfa1 fimbriae of Porphyromonas gingivalis on the progression of bone resorption remains unclear, especially compared with another fimbriae, FimA. We investigated the effect of Mfa1 on osteoclastogenesis together with FimA. We also… read more here.
Keywords: toll like; mfa1; osteoclastogenesis; porphyromonas gingivalis ... See more keywords