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   Articles with "mfolfirinox" as a keyword



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Primary systemic therapy in resectable pancreatic ductal adenocarcinoma using mFOLFIRINOX: A pilot study

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recommendations! Published in 2018 at "Journal of Surgical Oncology"

DOI: 10.1002/jso.24872

Abstract: Surgery followed by gemcitabine and/or a fluoropyrimidine is standard therapy for resectable PDAC. mFOLFIRINOX (oxaliplatin 85 mg/m2, irinotecan 180 mg/m2, leucovorin 400 mg/m2 Day 1, 5‐FU 2400 mg/m2 × 48 h IV, peg‐filgrastim 6 mg SQ day 3, every 14 days) has substantial… read more here.

Keywords: systemic therapy; resectable pancreatic; primary systemic; mfolfirinox ... See more keywords
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Phase II trial of preoperative modified FOLFIRINOX (mFOLFIRINOX) followed by postoperative gemcitabine (GEM) in patients (pts) with borderline resectable (BR) and locally advanced (LA) pancreatic ductal adenocarcinoma (PDAC)

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recommendations! Published in 2019 at "Annals of Oncology"

DOI: 10.1093/annonc/mdz247.016

Abstract: Abstract Background mFOLFIRINOX and GEM are standard chemotherapy for pts with PDAC. This single-arm phase 2 trial assessed the efficacy and safety of perioperative chemotherapy consisted of preoperative mFOLFIRINOX and postoperative GEM in pts with… read more here.

Keywords: pts pdac; gem; mfolfirinox; rate ... See more keywords
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Phase II trial of preoperative modified FOLFIRINOX (mFOLFIRINOX) followed by postoperative gemcitabine (GEM) in patients (pts) with borderline resectable pancreatic ductal adenocarcinomas (BR-PDAC).

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recommendations! Published in 2019 at "Journal of Clinical Oncology"

DOI: 10.1200/jco.2019.37.4_suppl.342

Abstract: 342 Background: mFOLFIRINOX and GEM are standard chemotherapy for metastatic and resected PDAC, respectively. This phase 2 trial assessed the efficacy and safety of perioperative chemotherapy consisted of preoperative mFOLFIRINOX and postoperative GEM in pts… read more here.

Keywords: pdac; mfolfirinox; phase trial; surgery ... See more keywords
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A randomised phase II study of modified FOLFIRINOX versus gemcitabine plus nab-paclitaxel for locally advanced pancreatic cancer (JCOG1407).

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recommendations! Published in 2022 at "European journal of cancer"

DOI: 10.2139/ssrn.4263813

Abstract: AIM We compared the efficacy of modified 5-fluorouracil, leucovorin, irinotecan, and oxaliplatin (mFOLFIRINOX) with that of gemcitabine plus nab-paclitaxel (GnP) for locally advanced pancreatic cancer (LAPC). METHODS Patients with untreated LAPC were randomly assigned (1:1)… read more here.

Keywords: gemcitabine plus; plus nab; gnp; gemcitabine ... See more keywords