The MK2 cascade mediates transient alteration in mGluR‐LTD and spatial learning in a murine model of Alzheimer's disease
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DOI: 10.1111/acel.13717
Abstract: A key aim of Alzheimer disease research is to develop efficient therapies to prevent and/or delay the irreversible progression of cognitive impairments. Early deficits in long‐term potentiation (LTP) are associated with the accumulation of amyloid… read more here.
Keywords: mglur ltd; mk2 cascade; mglur; alzheimer disease ... See more keywords
Selective Recruitment of Presynaptic and Postsynaptic Forms of mGluR-LTD
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Synaptic Neuroscience"
DOI: 10.3389/fnsyn.2022.857675
Abstract: In area CA1 of the hippocampus, long-term depression (LTD) can be induced by activating group I metabotropic glutamate receptors (mGluRs), with the selective agonist DHPG. There is evidence that mGluR-LTD can be expressed by either… read more here.
Keywords: mglur ltd; selective recruitment; presynaptic postsynaptic; postsynaptic forms ... See more keywords