Articles with "mglur1" as a keyword



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Upregulation of Striatal Metabotropic Glutamate Receptor Subtype 1 (mGluR1) in Rats with Excessive Glutamate Release Induced by N-Acetylcysteine

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Published in 2022 at "Neurotoxicity Research"

DOI: 10.1007/s12640-021-00449-4

Abstract: The aim of this study is to investigate the changes in expression of metabotropic glutamate (Glu) receptor subtype 1 (mGluR1), a key molecule involved in neuroexcitetoxicity, during excessive Glu release in the brain by PET… read more here.

Keywords: glu; release; metabotropic glutamate; receptor subtype ... See more keywords
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The Probability of Neurotransmitter Release Governs AMPA Receptor Trafficking via Activity-Dependent Regulation of mGluR1 Surface Expression

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Published in 2018 at "Cell Reports"

DOI: 10.1016/j.celrep.2018.12.010

Abstract: A major mechanism contributing to synaptic plasticity involves alterations in the number of AMPA receptors (AMPARs) expressed at synapses. Hippocampal CA1 synapses, where this process has been most extensively studied, are highly heterogeneous with respect… read more here.

Keywords: probability neurotransmitter; mglur1; neurotransmitter release; activity ... See more keywords
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A group I metabotropic glutamate receptor controls synaptic gain between rods and rod bipolar cells in the mouse retina

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Published in 2018 at "Physiological Reports"

DOI: 10.14814/phy2.13885

Abstract: The canonical mGluR6‐Trpm1 pathway that generates the sign‐inverting signal between photoreceptors and ON bipolar cells has been well described. However, one type of ON bipolar cell, the rod bipolar cell (RBC), additionally is thought to… read more here.

Keywords: controls synaptic; gain; group; bipolar cells ... See more keywords
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Metabotropic Glutamate Receptors 1 Regulates Rat Carotid Body Response to Acute Hypoxia via Presynaptic Mechanism

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Published in 2021 at "Frontiers in Neuroscience"

DOI: 10.3389/fnins.2021.741214

Abstract: Background: The carotid body (CB) plays a critical role in oxygen sensing; however, the role of glutamatergic signaling in the CB response to hypoxia remains uncertain. We previously found that functional multiple glutamate transporters and… read more here.

Keywords: response; response acute; mglur1; hypoxia ... See more keywords