Ketamine-induced reduction in mGluR5 availability is associated with an antidepressant response: an [11C]ABP688 and PET imaging study in depression
Sign Up to like & getrecommendations! Published in 2018 at "Molecular psychiatry"
DOI: 10.1038/mp.2017.58
Abstract: The mechanisms of action of the rapid antidepressant effects of ketamine, an N-methyl-D-aspartate glutamate receptor antagonist, have not been fully elucidated. This study examined the effects of ketamine on ligand binding to a metabotropic glutamatergic… read more here.
Keywords: reduction; mglur5; ketamine induced; mglur5 availability ... See more keywords