Articles with "mgr" as a keyword



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Efficacy and Safety of Glycopyrrolate/Formoterol Metered Dose Inhaler Formulated Using Co‐Suspension Delivery Technology in Patients With COPD

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Published in 2017 at "Chest"

DOI: 10.1016/j.chest.2016.11.028

Abstract: Background: Long‐acting muscarinic antagonist (LAMA)/long‐acting &bgr;2‐agonist (LABA) combinations are a treatment option for patients with COPD who continue to have symptoms despite treatment with a LAMA or a LABA alone. The Efficacy and Safety of… read more here.

Keywords: efficacy safety; mdi; inhaler; safety ... See more keywords
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Propofol improves colonic but impairs hepatic mitochondrial function in tissue homogenates from healthy rats

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Published in 2019 at "European Journal of Pharmacology"

DOI: 10.1016/j.ejphar.2019.04.031

Abstract: ABSTRACT Evidence suggests that propofol infusion syndrome (PRIS) is caused by an altered mitochondrial function. The aim of this study was to examine the effects of propofol and the vehicle MCT on mitochondrial function in… read more here.

Keywords: mct; propofol mct; mitochondrial function; complex ... See more keywords
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E‐cigarettes as a source of toxic and potentially carcinogenic metals

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Published in 2017 at "Environmental Research"

DOI: 10.1016/j.envres.2016.09.026

Abstract: Background and aims The popularity of electronic cigarette devices is growing worldwide. The health impact of e‐cigarette use, however, remains unclear. E‐cigarettes are marketed as a safer alternative to cigarettes. The aim of this research… read more here.

Keywords: nickel chromium; source toxic; cigarettes source; toxic ... See more keywords
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Impact of particle size on distribution and human exposure of flame retardants in indoor dust

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Published in 2018 at "Environmental Research"

DOI: 10.1016/j.envres.2017.12.014

Abstract: Abstract The effect of dust particle size on the distribution and bioaccessibility of flame retardants (FRs) in indoor dust remains unclear. In this study, we analyzed 20 FRs (including 6 organophosphate flame retardants (OPFRs), 8… read more here.

Keywords: bioaccessibility; size; dust; flame retardants ... See more keywords
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Monolith weak affinity chromatography for &mgr;g‐protein‐ligand interaction study

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Published in 2019 at "Journal of Pharmaceutical and Biomedical Analysis"

DOI: 10.1016/j.jpba.2019.01.012

Abstract: &NA; Affinity monolith columns of 375 nL (effective length 8.5 cm, internal diameter 75 &mgr;m) were developed for protein‐ligand affinity investigations needing only 3 &mgr;g of human serum albumin (HSA). To promote specific interactions and… read more here.

Keywords: protein; affinity; weak affinity; affinity chromatography ... See more keywords
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Phase-amplitude coupled persistent theta and gamma oscillations in rat primary motor cortex in vitro

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Published in 2017 at "Neuropharmacology"

DOI: 10.1016/j.neuropharm.2017.04.009

Abstract: ABSTRACT In vivo, theta (4–7 Hz) and gamma (30–80 Hz) neuronal network oscillations are known to coexist and display phase‐amplitude coupling (PAC). However, in vitro, these oscillations have for many years been studied in isolation.… read more here.

Keywords: gamma oscillations; theta gamma; mgr; vitro ... See more keywords

Local and hematological alterations induced by Philodryas olfersii snake venom in mice

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Published in 2017 at "Toxicon"

DOI: 10.1016/j.toxicon.2017.03.013

Abstract: &NA; Envenomation by the South American opisthoglyphous snake Philodryas olfersii causes local pain, edema, erythema and ecchymosis; systemic envenomation is rare. In this work, we examined the inflammatory activity of P. olfersii venom (10, 30… read more here.

Keywords: philodryas olfersii; venom; hematological alterations; venom mice ... See more keywords
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Mechanistic insights into functional characteristics of native crotamine

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Published in 2018 at "Toxicon"

DOI: 10.1016/j.toxicon.2018.03.007

Abstract: &NA; The chemical composition of snake venoms is a complex mixture of proteins and peptides that can be pharmacologically active. Crotamine, a cell‐penetrating peptide, has been described to have antimicrobial properties and it exerts its… read more here.

Keywords: mgr mgr; platelet aggregation; crotamine; mgr ... See more keywords
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Assessment of Occupational Exposure to Bisphenol A in Five Different Production Companies in Finland

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Published in 2017 at "Annals of Work Exposures and Health"

DOI: 10.1093/annweh/wxw006

Abstract: &NA; The aim of the study was to assess occupational exposure to bisphenol A in Finland. Five companies took part in the research project: two paint factories (liquid and powder paints), a composite product factory,… read more here.

Keywords: bisphenol; exposure; urine samples; exposure bisphenol ... See more keywords
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PD-006 Higher Vedolizumab Trough Levels Associated with Remission in Inflammatory Bowel Disease (IBD) Patients During Maintenance Therapy

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Published in 2017 at "Inflammatory Bowel Diseases"

DOI: 10.1097/01.mib.0000512530.93619.36

Abstract: Background: Vedolizumab (VDZ) is an anti-integrin biologic used in the treatment of ulcerative colitis (UC) and Crohn's disease (CD). In clinical trials, higher trough levels at weeks 6 and 52 were associated with higher rates… read more here.

Keywords: maintenance therapy; vdz; remission; vdz levels ... See more keywords
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Peripherally Acting &mgr;-Opioid Receptor Agonists Attenuate Ongoing Pain-associated Behavior and Spontaneous Neuronal Activity after Nerve Injury in Rats

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Published in 2018 at "Anesthesiology"

DOI: 10.1097/aln.0000000000002191

Abstract: Background: Ongoing neuropathic pain is difficult to treat. The authors examined whether dermorphin [D-Arg2, Lys4] (1–4) amide, a peripherally acting µ-opioid receptor agonist, attenuates ongoing pain-associated manifestations after nerve injury in rats and mice. Methods:… read more here.

Keywords: lys4 amide; peripherally acting; arg2 lys4; dermorphin arg2 ... See more keywords