The Effect of Lunasin on Receptor Activator of Nuclear Factor Kappa‐B Ligand−mediated Osteoclast Formation from RAW 264.7 Cells
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Endodontics"
DOI: 10.1016/j.joen.2018.02.023
Abstract: Introduction: To date, no study has investigated the antiresorptive property of lunasin. Hence, the present study aimed to assess the ability of lunasin to inhibit the osteoclast formation using RAW 264.7 cells. We hypothesized that… read more here.
Keywords: mgr mol; osteoclast formation; lunasin; raw 264 ... See more keywords
Comparison of the behavioral responses induced by phenylalkylamine hallucinogens and their tetrahydrobenzodifuran (“FLY”) and benzodifuran (“DragonFLY”) analogs
Sign Up to like & getrecommendations! Published in 2019 at "Neuropharmacology"
DOI: 10.1016/j.neuropharm.2018.10.037
Abstract: &NA; In recent years, rigid analogs of phenylalkylamine hallucinogens have appeared as recreational drugs. Examples include 2‐(8‐bromo‐2,3,6,7‐tetrahydrobenzo[1,2‐b:4,5‐b′]difuran‐4‐yl)ethan‐1‐amine (2C‐B‐FLY) and 1‐(8‐bromobenzo[1,2‐b;4,5‐b']difuran‐4‐yl)‐2‐aminopropane (Bromo‐DragonFLY, DOB‐DFLY). Although some rigid compounds such as DOB‐DFLY reportedly have higher potency than their… read more here.
Keywords: mgr mol; potency; fly; ed50 mgr ... See more keywords
A16561 Hypo-uricemic effect of losartan depending on a gender
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Hypertension"
DOI: 10.1097/01.hjh.0000548844.85922.f5
Abstract: Objectives: To examine hypo-uricemic efficacy of losartan and its combination with hydrochlorothiazide (HTZ) in hypertensive patients depending on a gender. Methods: The study included 505 patients: 165 men (32%) and 340 women (57%) 60.9 ± 5.0 years… read more here.
Keywords: mgr mol; uric acid; gender; hypo uricemic ... See more keywords
Evaluation of the Novel Methotrexate Architect Chemiluminescent Immunoassay: Clinical Impact on Pharmacokinetic Monitoring
Sign Up to like & getrecommendations! Published in 2017 at "Therapeutic Drug Monitoring"
DOI: 10.1097/ftd.0000000000000434
Abstract: Background: Fluorescence polarization immunoassay (FPIA) has probably been the most widely used technique for the determination of methotrexate (MTX) concentrations in clinical laboratories. After its replacement by a novel architect chemiluminescent microparticle immunoassay (CMIA), it… read more here.
Keywords: mgr mol; methotrexate; architect chemiluminescent; mtx ... See more keywords
In vitro and physiologically‐based pharmacokinetic based assessment of drug–drug interaction potential of canagliflozin
Sign Up to like & getrecommendations! Published in 2017 at "British Journal of Clinical Pharmacology"
DOI: 10.1111/bcp.13186
Abstract: Aims Canagliflozin is a recently approved drug for use in the treatment of type 2 diabetes. The potential for canagliflozin to cause clinical drug–drug interactions (DDIs) was assessed. Methods DDI potential of canagliflozin was investigated… read more here.
Keywords: mgr mol; drug; potential canagliflozin; interaction ... See more keywords
Effect of Histone Deacetylase Inhibition on the Expression of Multidrug Resistance-associated Protein 2 in a Human Placental Trophoblast Cell Line
Sign Up to like & getrecommendations! Published in 2017 at "Chinese Medical Journal"
DOI: 10.4103/0366-6999.206352
Abstract: Background: Placental multidrug resistance-associated protein 2 (MRP2), encoded by ABCC2 gene in human, plays a significant role in regulating drugs’ transplacental transfer rates. Studies on placental MRP2 regulation could provide more therapeutic targets for individualized… read more here.
Keywords: mgr mol; cell line; inhibition; mrp2 expression ... See more keywords