Comparative evaluation of involved free light chain and monoclonal spike as markers for progression from monoclonal gammopathy of undetermined significance to multiple myeloma
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DOI: 10.1002/ajh.25999
Abstract: Monoclonal gammopathy of undetermined significance (MGUS) is a premalignant clonal plasma cell disorder, with a 1% yearly risk of progression to multiple myeloma (MM). Evolution of M‐spike and serum free light chain (sFLC) during follow‐up… read more here.
Keywords: monoclonal gammopathy; risk; spike; progression ... See more keywords
How to resolve a clinical and molecular puzzle: concomitant monoclonal gammopathy of undetermined significance (MGUS) with neutrophilia and clonal hematopoiesis of indeterminate potential (CHIP)
Sign Up to like & getrecommendations! Published in 2019 at "Annals of Hematology"
DOI: 10.1007/s00277-019-03786-9
Abstract: Dear Editor, The association between plasma cell (PC) neoplasms (PCN) and neutrophilia is a rare but well-known phenomenon [1–3]. CHIP designates asymptomatic presence of clones in the peripheral blood and/or the bone marrow carrying somatic… read more here.
Keywords: monoclonal gammopathy; mgus neutrophilia; cell; mgus ... See more keywords
Characteristics and prognosis of patients with non-immunoglobulin-M monoclonal gammopathy of undetermined significance: a retrospective study
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DOI: 10.1007/s12185-018-2555-7
Abstract: Non-immunoglobulin (Ig)-M monoclonal gammopathy of undetermined significance (MGUS) is a precursor lesion with the potential to evolve into a malignant plasma cell neoplasm. The prevalence of MGUS differs by ethnicity and is lower in the… read more here.
Keywords: monoclonal gammopathy; mgus; patients non; study ... See more keywords
Prognosis of young patients with monoclonal gammopathy of undetermined significance (MGUS)
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DOI: 10.1038/s41408-021-00406-6
Abstract: Monoclonal gammopathy of undetermined significance (MGUS) is rare in young patients (age read more here.
Keywords: young patients; immune related; risk progression; mgus ... See more keywords
Multiple myeloma patients-derived exosomes as a potential new clinical tool
Sign Up to like & getrecommendations! Published in 2019 at "Annals of Medicine"
DOI: 10.1080/07853890.2018.1561905
Abstract: Introduction: Multiple Myeloma (MM) is a highly heterogeneous neoplasia, usually preceded by a monoclonal-gammopathy-of-undetermined-significance (MGUS). MM has a diverse clinical presentation, variable response to treatment and outcome. Poor response to novel drugs or extramedullary-disease (EMD)… read more here.
Keywords: median exo; response; treatment; disease ... See more keywords
Prevalence of monoclonal gammopathy of undetermined significance in Shenzhen, China
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DOI: 10.1080/16078454.2024.2352686
Abstract: ABSTRACT Background Data on the prevalence of monoclonal gammopathy of undetermined significance (MGUS) in China are very limited. Our aim was to determine the prevalence and clinical characteristics of MGUS in a large Chinese population.… read more here.
Keywords: monoclonal gammopathy; mgus; prevalence monoclonal; gammopathy undetermined ... See more keywords
B-075 Evaluation of patients with monoclonal gammopathy of undetermined significance using Optilite Freelite assays
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DOI: 10.1093/clinchem/hvae106.437
Abstract: Monoclonal gammopathy of undetermined significance (MGUS) is a pre-malignant disorder with a progression risk to multiple myeloma of 1% per year. Patients with MGUS may produce monoclonal intact immunoglobulins (Ig) and/or free light chains (FLC).… read more here.
Keywords: optilite freelite; monoclonal gammopathy; mgus; freelite assays ... See more keywords
Monoclonal Gammopathy of Undetermined Significance After Kidney Transplantation: Single-Center Experience
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DOI: 10.1097/tp.0000000000001884
Abstract: Background Monoclonal gammopathy of undetermined significance (MGUS) is an asymptomatic premalignant plasma cell disorder. Prevalence and clinical outcomes of MGUS in kidney transplant (KT) recipients have been previously reported in few studies with conflicting results.… read more here.
Keywords: monoclonal gammopathy; undetermined significance; gammopathy undetermined; mgus ... See more keywords
Association Between Monoclonal Gammopathy of Undetermined Significance and Cardiovascular Disease Risk: A Veterans Health Administration Study.
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DOI: 10.1161/jaha.125.042187
Abstract: BACKGROUND Monoclonal gammopathy of undetermined significance (MGUS) is associated with an increased risk of cardiovascular disease (CVD). However, its potential to provide additional prognostic information beyond traditional CVD risk assessments remains unknown. This study aimed… read more here.
Keywords: mgus; cvd; risk; cardiovascular disease ... See more keywords
Regression of Intermediate-High Risk Monoclonal Gammopathy of Undetermined Significance (MGUS) With Long-term Use of Curcumin: A Case Report
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DOI: 10.1177/15347354241242099
Abstract: Patients with intermediate-high risk MGUS are not offered therapeutic options to date and standard of care remains observation with re-evaluations of the patient every 3 to 6 months. Given the persistent risk of progression as well… read more here.
Keywords: regression intermediate; risk monoclonal; mgus; intermediate high ... See more keywords
Natural History of Asymptomatic IgM Monoclonal Gammopathies: Impact of the Bone Marrow Aspiration into the Classification and Prognosis
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DOI: 10.1182/blood-2018-99-115038
Abstract: Introduction: As in multiple myeloma, Waldenström macroglobulinemia (WM) is preceded by an asymptomatic phase, mainly as monoclonal gammopathy of undetermined significance (MGUS) or by a smoldering WM (SWM) phase. It has recently been reported that… read more here.
Keywords: igm monoclonal; igm mgus; swm; progression ... See more keywords