Comparative evaluation of involved free light chain and monoclonal spike as markers for progression from monoclonal gammopathy of undetermined significance to multiple myeloma
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DOI: 10.1002/ajh.25999
Abstract: Monoclonal gammopathy of undetermined significance (MGUS) is a premalignant clonal plasma cell disorder, with a 1% yearly risk of progression to multiple myeloma (MM). Evolution of M‐spike and serum free light chain (sFLC) during follow‐up… read more here.
Keywords: monoclonal gammopathy; risk; spike; progression ... See more keywords
How to resolve a clinical and molecular puzzle: concomitant monoclonal gammopathy of undetermined significance (MGUS) with neutrophilia and clonal hematopoiesis of indeterminate potential (CHIP)
Sign Up to like & getrecommendations! Published in 2019 at "Annals of Hematology"
DOI: 10.1007/s00277-019-03786-9
Abstract: Dear Editor, The association between plasma cell (PC) neoplasms (PCN) and neutrophilia is a rare but well-known phenomenon [1–3]. CHIP designates asymptomatic presence of clones in the peripheral blood and/or the bone marrow carrying somatic… read more here.
Keywords: monoclonal gammopathy; mgus neutrophilia; cell; mgus ... See more keywords
Characteristics and prognosis of patients with non-immunoglobulin-M monoclonal gammopathy of undetermined significance: a retrospective study
Sign Up to like & getrecommendations! Published in 2018 at "International Journal of Hematology"
DOI: 10.1007/s12185-018-2555-7
Abstract: Non-immunoglobulin (Ig)-M monoclonal gammopathy of undetermined significance (MGUS) is a precursor lesion with the potential to evolve into a malignant plasma cell neoplasm. The prevalence of MGUS differs by ethnicity and is lower in the… read more here.
Keywords: monoclonal gammopathy; mgus; patients non; study ... See more keywords
Prognosis of young patients with monoclonal gammopathy of undetermined significance (MGUS)
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DOI: 10.1038/s41408-021-00406-6
Abstract: Monoclonal gammopathy of undetermined significance (MGUS) is rare in young patients (age read more here.
Keywords: young patients; immune related; risk progression; mgus ... See more keywords
Multiple myeloma patients-derived exosomes as a potential new clinical tool
Sign Up to like & getrecommendations! Published in 2019 at "Annals of Medicine"
DOI: 10.1080/07853890.2018.1561905
Abstract: Introduction: Multiple Myeloma (MM) is a highly heterogeneous neoplasia, usually preceded by a monoclonal-gammopathy-of-undetermined-significance (MGUS). MM has a diverse clinical presentation, variable response to treatment and outcome. Poor response to novel drugs or extramedullary-disease (EMD)… read more here.
Keywords: median exo; response; treatment; disease ... See more keywords
Monoclonal Gammopathy of Undetermined Significance After Kidney Transplantation: Single-Center Experience
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DOI: 10.1097/tp.0000000000001884
Abstract: Background Monoclonal gammopathy of undetermined significance (MGUS) is an asymptomatic premalignant plasma cell disorder. Prevalence and clinical outcomes of MGUS in kidney transplant (KT) recipients have been previously reported in few studies with conflicting results.… read more here.
Keywords: monoclonal gammopathy; undetermined significance; gammopathy undetermined; mgus ... See more keywords
Natural History of Asymptomatic IgM Monoclonal Gammopathies: Impact of the Bone Marrow Aspiration into the Classification and Prognosis
Sign Up to like & getrecommendations! Published in 2018 at "Blood"
DOI: 10.1182/blood-2018-99-115038
Abstract: Introduction: As in multiple myeloma, Waldenström macroglobulinemia (WM) is preceded by an asymptomatic phase, mainly as monoclonal gammopathy of undetermined significance (MGUS) or by a smoldering WM (SWM) phase. It has recently been reported that… read more here.
Keywords: igm monoclonal; igm mgus; swm; progression ... See more keywords
Association between Monoclonal Gammopathy and Rheumatoid Arthritis: A National Inpatient Sample (NIS) Study
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DOI: 10.1182/blood-2018-99-115672
Abstract: Introduction: Monoclonal gammopathy (MG) is a spectrum of conditions including monoclonal gammopathy of undetermined significance (MGUS) and multiple myeloma (MM). MM is the second most common hematologic malignancy. Despite advances in the treatment of MM… read more here.
Keywords: sample; monoclonal gammopathy; national inpatient; association ... See more keywords
Characterization of Circulating and Bone Marrow Derived Exosomes in Multiple Myeloma Patients
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DOI: 10.1182/blood-2018-99-117656
Abstract: Background: Multiple myeloma (MM) is characterized by clinical and biological heterogeneity, translating to variable outcome. High International Staging System (ISS), high risk cytogenetics, elevated LDH, poor response to novel drugs or extramedullary-disease (EMD) are associated… read more here.
Keywords: protein; multiple myeloma; exocargo; mgus ... See more keywords
Health Care Burden of Monogammopathy of Renal Significance
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DOI: 10.1182/blood-2020-139740
Abstract: Monoclonal gammopathy of undetermined significance (MGUS) is a premalignant, clonal plasma cell disorder, characterized by the presence of a monoclonal (M) protein in serum, read more here.
Keywords: mgus; advisory board; ckd; ckd stage ... See more keywords
Obesity and risk of monoclonal gammopathy of undetermined significance and progression to multiple myeloma: a population-based study.
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DOI: 10.1182/bloodadvances.2017007609
Abstract: All multiple myeloma (MM) cases are preceded by the premalignant state monoclonal gammopathy of undetermined significance (MGUS). Results from previous studies show a positive association between obesity and MM; however, the association between obesity and… read more here.
Keywords: monoclonal gammopathy; risk; multiple myeloma; obesity ... See more keywords