TGIF1 homeodomain interacts with Smad MH1 domain and represses TGF-β signaling
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DOI: 10.1093/nar/gky680
Abstract: Abstract TGIF1 is a multifunctional protein that represses TGF-β-activated transcription by interacting with Smad2-Smad4 complexes. We found that the complex structure of TGIF1–HD bound to the TGACA motif revealed a combined binding mode that involves… read more here.
Keywords: dna; tgif1; represses tgf; mh1 domain ... See more keywords