Upregulated mH2A1 serves as an unfavorable prognostic indicator and promotes the progress of hepatocellular carcinoma (HCC).
Sign Up to like & getrecommendations! Published in 2020 at "Life sciences"
DOI: 10.1016/j.lfs.2020.118576
Abstract: PURPOSE To investigate the role and prognostic value of mH2A1 in the progression of hepatocellular carcinoma (HCC). METHODS Basing on the Cancer Genome Atlas-Liver Hepatocellular Carcinoma (TCGA-LIHC) and GEO datasets, the gene expression of mH2A1… read more here.
Keywords: hepatocellular carcinoma; hcc; expression; progression ... See more keywords
SirT7 auto-ADP-ribosylation regulates glucose starvation response through mH2A1
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DOI: 10.1126/sciadv.aaz2590
Abstract: SirT7 is a dual enzyme that regulates energy deprivation response through a functional interaction with histone variant mH2A1. Sirtuins are key players of metabolic stress response. Originally described as deacetylases, some sirtuins also exhibit poorly… read more here.
Keywords: sirt7 auto; glucose starvation; response; mh2a1 ... See more keywords